Porth’s Essentials of Pathophysiology does what other traditional pathophysiology texts have failed to achieve: it makes foundational concepts clear, engaging, and clinically meaningful from day one. Written by experienced nurse educators, Porth’s Essentials of Pathophysiology, 6th Edition, focuses on what students need to know — not just what they can memorize, helping them connect core concepts across diseases, body systems, and real-world practice.
The result is a streamlined, highly teachable resource that removes unnecessary detail while strengthening conceptual understanding. Key topics like inflammation and immunity are positioned as foundational threads throughout the book, enabling students to apply what they learn across conditions and courses.
This isn’t just a textbook students get through; it’s one they return to. With clearer explanations, more relevant visuals, integrated A&P review, and a deliberate focus on clinical reasoning, students build confidence in both comprehension and application.
For instructors, the value is just as clear: a text that supports active learning, reduces student overwhelm, and improves retention of essential concepts tied to NCLEX® success and clinical judgment.
If your goal is not just coverage of pathophysiology, but also encouraging curiosity, ensuring comprehension, and delivering long-term retention, Porth’s Essentials of Pathophysiology delivers for you.
UNIT 1: Basics of Pathophysiology
Chapter 1: Concepts of Health and Disease
UNIT 2: Cellular and Biologic Processes
Chapter 2: Cell and Tissue Characteristics
Chapter 3: Cellular Adaptation and Injury
UNIT 3: Integrated Processes
Chapter 4: Stress and Adaptation
Chapter 5: Fluid, Electrolyte, and Acid-Base Balance
Chapter 6: Genetic Influences and Alterations
Chapter 7: Neoplasia
Chapter 8: Nutritional Alterations
Chapter 9: Immunity and Inflammation
Chapter 10: Mechanisms of Infectious Disease
UNIT 4: Disorders of Skin Integrity and Function
Chapter 11: The Integumentary System
UNIT 5: Disorders of Neurologic and Sensory Function
Chapter 12: Somatosensory Function, Pain, and Sleep
Chapter 13: Disorders of Motor Function
Chapter 14: Disorders of Brain Function
Chapter 15: Disorders of Thought, Emotion, and Memory
Chapter 16: Disorders of Vision, Hearing, and Vestibular Function
UNIT 6: Disorders of the Hematopoietic System
Chapter 17: Essentials of Blood Composition and Hematopoiesis
Chapter 18: Disorders of Hemostasis and Red Blood Cells
Chapter 19: Disorders of White Blood Cells and Lymphoid Tissues
UNIT 7: Disorders of Cardiovascular Function
Chapter 20: Disorders of Blood Flow and Blood Pressure Regulation
Chapter 21: Disorders of Cardiac Function and Shock
Chapter 22: Disorders of Cardiac Conduction and Rhythm
UNIT 8: Disorders of Respiratory Function
Chapter 23: Disorders of Ventilation and Gas Exchange
Chapter 24: Etiologic and Structural Disorders of the Respiratory System
UNIT 9: Disorders of Renal Function
Chapter 25: Foundations of Renal Structure, Function, and Development
Chapter 26: Primary and Acquired Renal Disorders
Chapter 27: Acute Kidney Injury, Chronic Kidney Disease, and Lower Urinary Tract Dysfunction
UNIT 10: Disorders of Gastrointestinal Function
Chapter 28: Disorders of Gastrointestinal Function
Chapter 29: Disorders of Hepatobiliary and Exocrine Pancreas Function
UNIT 11: Disorders of Endocrine Function
Chapter 30: Endocrine Disorders of Growth and Metabolism
UNIT 12: Disorders of Reproductive Function
Chapter 31: Reproductive Function, Infertility, and Sexually Transmitted Infections
Chapter 32: Disorders of the Reproductive System
UNIT 13: Disorders of Musculoskeletal Function
Chapter 33: Developmental, Traumatic, and Neoplastic Disorders of the Musculoskeletal System
Chapter 34: Metabolic, Inflammatory, and immune-Mediated Disorders of the Musculoskeletal System
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