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# Block’s Disinfection, Sterilization, and Preservation

9781975153960
ISBN/ISSN
9781975153960
Publication Date
July 1, 2019
2019-07-1
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9781975153960
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• Description
With more international contributors than ever before, Block’s Disinfection, Sterilization, and Preservation, 6th Edition, is the first new edition in nearly 20 years of the definitive technical manual for anyone involved in physical and chemical disinfection and sterilization methods. The book focuses on disease prevention—rather than eradication—and has been thoroughly updated with new information based on recent advances in the field and understanding of the risks, the technologies available, and the regulatory environments.
• International authorship has expanded, and editors and contributors have extensive backgrounds in antimicrobial control of infection risks.
• Discusses new understandings of microbes and how to manage them through disinfection and prevention.
• Content addresses chemical types of disinfectants/sterilants, physical disinfection/sterilization technologies, test methodologies, and more.
• eBook features a selection of full-color figures.
• Ideal for academic investigation as well as for practical use across industrial and regulatory applications.
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• Specs
Edition
6
ISBN/ISSN
9781975153960
Product Format
VST ePub3
Trim Size
8 3/8 x 10 7/8
Table
0
Edition
6
Publication Date
July 1, 2019
• Gerald McDonnell
• Table of contents
Contents
C o n t r i b u t o r s v i i i
P r e f a c e x v i
PART I: INTRODUCTION
1. Historical Perspective . . . . . . . . . . . . . . . . . .1
Eamonn V . Hoxey
2. Defi nition of Terms . . . . . . . . . . . . . . . . . . . .9
Gerald McDonnell
PART II: FUNDAMENTAL PRINCIPLES OF
ACTIVITY
3. Microorganisms and Resistance . . . . . . . . .23
Gerald McDonnell
4. Bacterial Resistance to Biocides . . . . . . . . .44
Jean-Yves Maillard
5. Principles of Antimicrobial Activity. . . . . . .68
Gerald McDonnell and Joyce M. Hansen
6. The Impact of Formulary Components
on Antimicrobial Products. . . . . . . . . . . . .120
Peter A. Burke and José A. Ramirez
7. Kinetics of the Inactivation of
Microorganisms. . . . . . . . . . . . . . . . . . . . .140
Alfredo C. Rodríguez
8. Importance and Processes of
Cleaning . . . . . . . . . . . . . . . . . . . . . . . . . .160
Rizwan Sharnez
PART III: DISINFECTION BY
ANTIMICROBIAL TYPES
9. Ultraviolet Disinfection . . . . . . . . . . . . . . .171
Ernest R. Blatchley III and Thomas P . Coohill
10. Nonionizing Radiation: Microwave
Radiation, Infrared Radiation, and
Pulsed Light. . . . . . . . . . . . . . . . . . . . . . . .192
Mark A. Smith
11. Microbial Inactivation Kinetics and
Heat Disinfection. . . . . . . . . . . . . . . . . . . .205
Patrick J. McCormick, James J. Kaiser, and
Michael J. Schoene
12. Acids and Alkalis . . . . . . . . . . . . . . . . . . . .243
Md Ramim Tanver Rahman, Luyan Z. Ma, and
Mohammad Shafi ur Rahman
13. Antimicrobial Dyes . . . . . . . . . . . . . . . . . .252
Mark Wainwright
14. Essential Oils. . . . . . . . . . . . . . . . . . . . . . .268
Katherine A. Hammer and Christine F . Carson
15. Chlorine and Chlorine Compounds . . . . .280
Nancy A. Falk, Marisa Macnaughtan, Atefeh Taheri, and
William McCormick
16. Iodine and Iodine-Containing
Compounds. . . . . . . . . . . . . . . . . . . . . . . .306
Paul L. Bigliardi, Maren Eggers, Marc Cataldo, Ram Kapil,
Manjunath Shet, and Michael K. Pugsley
17. Bromine and Bromine-Releasing
Biocides. . . . . . . . . . . . . . . . . . . . . . . . . . .332
Jonathan N. Howarth and Michael S. Harveyvi Contents
34. Plasma Sterilization . . . . . . . . . . . . . . . . . .702
Akikazu Sakudo, Hideharu Shintani, and
Yagyu Yoshihito
35. Nitrogen Dioxide . . . . . . . . . . . . . . . . . . .726
David Opie and Evan Goulet
36. Formaldehyde . . . . . . . . . . . . . . . . . . . . . .756
Allan Bennett and Thomas Pottage
PART V: PRESERVATION
37. Prevention of Infection From
Food and Water . . . . . . . . . . . . . . . . . . . .765
Christon J. Hurst and Gerald McDonnell
38. Preservation of Industrial
Products and Processes . . . . . . . . . . . . . .780
Tony A. Rook
39. Preservation of Pharmaceutical
Dosage Forms. . . . . . . . . . . . . . . . . . . . . .795
Patrick J. Crowley and David P . Elder
40. Cosmetic Preservatives and
Preservation . . . . . . . . . . . . . . . . . . . . . . .822
Philip A. Geis
41. Sterile Packaging. . . . . . . . . . . . . . . . . . . .835
Thierry Wagner, Dan B. Floyd, Michael H. Scholla, and
Jane E. Severin
PART VI: MEDICAL AND HEALTH-
RELATED APPLICATIONS
42. Hand Hygiene . . . . . . . . . . . . . . . . . . . . . .859
Günter Kampf
43. Surgical Antisepsis . . . . . . . . . . . . . . . . . .879
Gerald McDonnell
44. Infection Prevention for
Skin and Burns. . . . . . . . . . . . . . . . . . . . . .899
Gerald McDonnell
45. Oral and Mucous Membrane
Treatments . . . . . . . . . . . . . . . . . . . . . . . .916
Prerna Gopal and Lipika Gopal Chugh
46. Laundry Hygiene . . . . . . . . . . . . . . . . . . . .930
Dirk P . Bockmühl and Marlitt Honisch
47. Processing of Reusable Medical
Devices . . . . . . . . . . . . . . . . . . . . . . . . . . .938
Emily Mitzel
48. Targeted Decontamination of
Environmental Surfaces in
Everyday Settings . . . . . . . . . . . . . . . . . . .960
Elizabeth A. Scott, Elizabeth Bruning, and
Mohammad Khalid Ijaz
18. Peroxygen Compounds . . . . . . . . . . . . . .352
John Matta, Maruti Sinha, Kris Murphy, and
Suranjan Roychowdhury
19. Alcohols. . . . . . . . . . . . . . . . . . . . . . . . . . .384
Günter Kampf and James W. Arbogast
20. Phenolic Compounds . . . . . . . . . . . . . . . .408
Sarah de Szalay and John A. Diemer
21. Surface-Active Agents . . . . . . . . . . . . . . .437
John J. Merianos and Gerald McDonnell
22. Chlorhexidine . . . . . . . . . . . . . . . . . . . . . .477
Vinod P . Menon
23. Aldehydes . . . . . . . . . . . . . . . . . . . . . . . . .507
Stephen A. Kelly, Sean P . Gorman, and
Brendan F . Gilmore
24. Copper Alloy Surfaces Kill Bacteria and
Reduce Infections . . . . . . . . . . . . . . . . . . .538
James H. Michel, Harold T. Michels, and
Corinne A. Michels
25. Silver and Silver Nanoparticles . . . . . . . . .549
Jean-Yves Maillard and Philippe Hartemann
26. Peptides, Enzymes, and
Bacteriophages . . . . . . . . . . . . . . . . . . . . .559
Suzana Meira Ribeiro, Osmar Nascimento Silva,
Bruna de Oliveira Costa, and Octávio Luiz Franco
27. Chlorine Dioxide . . . . . . . . . . . . . . . . . . . .570
Zhao Chen and Mark A. Czarneski
PART IV: STERILIZATION BY
ANTIMICROBIAL TYPES
28. Sterilization and Depyrogenation
by Heat . . . . . . . . . . . . . . . . . . . . . . . . . . .589
Daniel L. Prince and Derek J. Prince
29. Sterilization and Preservation by
Radiation . . . . . . . . . . . . . . . . . . . . . . . . . .609
John R. Logar and Elaine Daniell
30. Sterile Filtration of Liquids and Gases . . .630
Kerry Roche Lentine and Richard V . Levy
31. Ethylene Oxide Sterilization . . . . . . . . . . .660
Craig A. Wallace
32. Disinfection and Sterilization With
Hydrogen Peroxide. . . . . . . . . . . . . . . . . .671
Randal W. Eveland
33. Disinfection and Sterilization
Using Ozone . . . . . . . . . . . . . . . . . . . . . . .684
Linda K. Weavers, G. B. Wickramanayake,
Mikhail Shifrin, and Gerald McDonnellContents vii
62. Standard Microbiological Methods for
Antimicrobial Products in
North America. . . . . . . . . . . . . . . . . . . . .1252
Scott Steinagel and Elaine Black
63. Antimicrobial Test Methods in the
European Union . . . . . . . . . . . . . . . . . . .1269
Lionel Pineau
64. Bioburden Assessment and
Tests for Sterility . . . . . . . . . . . . . . . . . . .1277
Martell Winters and Trabue Bryans
65. Biological Indicators, Chemical
Indicators, and Parametric Release . . . .1297
Richard Bancroft
PART IX: MISCELLANEOUS TOPICS
66. Bacterial Endotoxin. . . . . . . . . . . . . . . . .1307
Kimbrell R. Darnell and Amy Jo Karren
67. Biofi lm and Biofi lm Control. . . . . . . . . . .1320
Joey S. Lockhart, Andre G. Buret, and Douglas W. Morck
68. Prions. . . . . . . . . . . . . . . . . . . . . . . . . . . .1337
Kurt Giles, Amanda L. Woerman, and Stanley B. Prusiner
69. Fungal Contamination in the Built
Environment: Shipping and Storage. . . .1352
Daniel L. Price and Donald G. Ahearn
70. Regulation of Preservation,
Disinfection, and Sterilization Agents,
Equipment, and Processes . . . . . . . . . . .1360
Eric L. Dewhurst, Helen E. Forsdyke, and Eamonn V . Hoxey
71. Federal Regulation of Liquid
Chemical Germicides and Healthcare
Sterilization by the US Food and Drug
Administration. . . . . . . . . . . . . . . . . . . . .1379
Elizabeth Claverie-Williams, Steven Elliott,
Clarence Murray III, and Elaine Mayhall
72. Regulation of Antimicrobial
Pesticides by the US Environmental
Protection Agency . . . . . . . . . . . . . . . . .1380
Stephen F . Tomasino, Tajah L. Blackburn, and
Jacqueline L. Hardy
73. Antimicrobial Surfaces . . . . . . . . . . . . . .1387
Nicola J. Irwin, Colin P . McCoy, Matthew P . Wylie,
and Sean P . Gorman
74. Nanotechnology for Disinfection and
Sterilization . . . . . . . . . . . . . . . . . . . . . . .1404
David W. Hobson
S u b je c t I n dex 1419
49. Basic Principles of Infection
Prevention and Control. . . . . . . . . . . . . . .979
Charles Edmiston Jr and Gwen Borlaug
50. Disinfection and Sterilization of
Living and Scaffold Tissue Engineered
Medical Products . . . . . . . . . . . . . . . . . . .994
Kelvin G.M. Brockbank and Alyce Linthurst Jones
51. Sterilization, Disinfection, and
Asepsis in Dentistry . . . . . . . . . . . . . . . .1008
Chris H. Miller and Charles John Palenik
52. Disinfection and Biosecurity in the
Prevention and Control of Disease in
Veterinary Medicine . . . . . . . . . . . . . . . 1034
Patrick J. Quinn, Bryan K. Markey, Finola C. Leonard,
and Eamonn S. FitzPatrick
53. Disinfection of Contact Lenses . . . . . . . .1107
Manal M. Gabriel and Donald G. Ahearn
54. Infectious Waste Management,
Treatment, and Disposal . . . . . . . . . . . . 1125
Lawrence G. Doucet
55. Reprocessing and Remanufacturing of
Single-Use Medical Devices . . . . . . . . . .1145
D. J. Vukelich
PART VII: INDUSTRIAL AND RESEARCH
APPLICATIONS
56. Food- and Waterborne
Microorganisms. . . . . . . . . . . . . . . . . . . .1153
Gerald McDonnell
57. Groundwater Purifi cation . . . . . . . . . . . 1183
Nicholas P . Cheremisinoff and Chris Brown
58. Aseptic Processing and Facilities
for the Control of Microbial
Contamination. . . . . . . . . . . . . . . . . . . . .1200
James E. Akers Jr
59. Safe Handling of Biological
Agents in the Laboratory . . . . . . . . . . . .1214
Alan J. Beswick, Brian Crook, and
Catherine Makison Booth
60. Control and Monitoring of
Microbiological Quality in Nonsterile
Manufacturing Facilities . . . . . . . . . . . . .1229
Amy Jo Karren
PART VIII: METHODS OF TESTING
61. Disinfectant Effi cacy Testing . . . . . . . . . .1241
Dan Klein
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