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Wyllie's Treatment of Epilepsy

Principles and Practice
Edition: 7
9781496397690
ISBN/ISSN:
9781496397690
Publication Date:
May 5, 2020
2020-05-5
9781496397690
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Comprehensive, yet accessible, Wyllie’s Treatment of Epilepsy: Principles and Practice has provided a detailed and cohesive overview of seizure disorders ...
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  • Comprehensive, yet accessible, Wyllie’s Treatment of Epilepsy: Principles and Practice has provided a detailed and cohesive overview of seizure disorders and treatment options through six well-regarded editions. The 7th Edition remains the definitive reference in the field with extensive updates from Dr. Elaine Wyllie and her team of world-renowned editors and authors. Ideal for both clinical reference and exam preparation, this single-volume work on contemporary epileptology is an indispensable resource for neurologists, epilepsy specialists and epilepsy neurosurgeons, neurology and neurosurgery residents and fellows, and neuropsychologists.
    • Features considerable new or significantly revised content reflecting the most current evidence-based treatment options.
    • Offers an in-depth review of all aspects of epileptology, including neuroimaging; epilepsy surgery; antiseizure medications; principles of electroencephalography; psychosocial impact, quality of life, and comorbidities; economics of epilepsy; and more.
    • Provides more than 500 CME-eligible review questions online, highlighting key concepts for the ABPN subspecialty exam and clinical practice.

    Enrich Your Ebook Reading Experience

    • Read directly on your preferred device(s),such as computer, tablet, or smartphone.
    • Easily convert to audiobook,powering your content with natural language text-to-speech. 
  • Edition
    7
    ISBN/ISSN
    9781496397690
    Product Format
    Hardcover Book
    Trim Size
    8 3/8 x 10 7/8
    Pages
    1096
    Edition
    7
    Publication Date
    May 5, 2020
    Weight
    5.75
  • Elaine Wyllie MD
    Elaine Wyllie MD
    Professor, Cleveland Clinic Lerner College of Medicine
    Pediatric Epilepsy Specialist, Cleveland Clinic
     
    Dr. Elaine Wyllie is a world renowned thought leader in neurology and epilepsy. She has been on the Castle Connolly list of America’s Best Doctors for many years, as well as on several other national and regional Top Doctors lists. Her many honors and awards include the highly competitive Award for Outstanding Work in Epilepsy Research from the Milken Family Foundation and the Cleveland Clinic Lifetime Achievement Award for Master Clinician.
     
  • ¦ ¦ CONTENTS
    PART I ¦ EPIDEMIOLOGY, GENETICS, AND MECHANISMS OF EPILEPTOGENESIS
    HOWARD P . GOODKIN, ASSOCIATE EDITOR • TOBIAS LODDENKEMPER, QUESTIONS EDITOR
    CHAPTER 1 Epidemiologic Aspects of Epilepsy 2
    CHRISTINE LINEHAN • ANNE T. BERG
    CHAPTER 2 The Natural History and Prognosis of Epilepsy 13
    DING DING
    CHAPTER 3 Experimental Models of Seizures and Mechanisms of Status Epilepticus and Epileptogenesis 18
    TIM A. BENKE • MOLLY M. HUNTSMAN • AMY BROOKS-KAYAL
    CHAPTER 4 Genetic Aspects of the Epilepsies 29
    ERIKA TAKLE AXEEN • ANNAPURNA PODURI
    CHAPTER 5 Pictorial Atlas of Epilepsy Substrates 36
    AJAY GUPTA • RICHARD A. PRAYSON
    PART II ¦ BASIC PRINCIPLES OF ELECTROENCEPHALOGRAPHY
    TOBIAS LODDENKEMPER, ASSOCIATE EDITOR, QUESTIONS EDITOR
    CHAPTER 6 Neurophysiologic Basis of the Electroencephalogram 53
    ERWIN-JOSEF SPECKMANN • CHRISTIAN E. ELGER • ALI GORJI
    CHAPTER 7 Localization and Field Determination in Electroencephalography 68
    RICHARD C. BURGESS
    CHAPTER 8 Electroencephalographic Atlas of Epileptiform Abnormalities 90
    SOHEYL NOACHTAR • ELAINE WYLLIE
    CHAPTER 9 Quality Standards and Logistics of Establishing an Epilepsy Monitoring Unit 130
    DEEPAK K. LACHHWANI
    PART III ¦ EPILEPTIC SEIZURES AND SYNDROMES
    SECTION A ¦ ELECTROCLINICAL SYNDROMES
    TOBIAS LODDENKEMPER, ASSOCIATE EDITOR, QUESTIONS EDITOR
    CHAPTER 10 The Revised Definition and Classification of Seizures and Epilepsies 137
    ROBERT S. FISHER • TOBIAS LODDENKEMPER
    CHAPTER 11 Seizure Types and Semiology 145
    CLAUDE STERIADE • PATRICK CHAUVEL • PRAKASH KOTAGAL
    CHAPTER 12 Epileptic Auras 161
    NORMAN K. SO
    CHAPTER 13 Focal Epileptogenic Networks 172
    DILEEP NAIR • JUAN C. BULACIO • PATRICK CHAUVEL
    CHAPTER 14 Electroclinical Syndromes of Infancy 183
    ELIA M. PESTANA KNIGHTCHAPTER 15 Electroclinical Syndromes in Childhood and Adolescence 200
    KATHERINE NICKELS • RENÉE SHELLHAAS • ELAINE WYLLIE • ELAINE C. WIRRELL
    CHAPTER 16 Continuous Spike-and-Wave During Sleep, Including Landau–Kleffner Syndrome 220
    IVÁN SÁNCHEZ FERNÁNDEZ • TOBIAS LODDENKEMPER
    CHAPTER 17 Epilepsy with Reflex Seizures 230
    DOROTHÉE G. A. KASTELEIJN-NOLST TRENITÉ
    SECTION B ¦ SPECIFIC ETIOLOGIES
    HOWARD P . GOODKIN, ASSOCIATE EDITOR • TOBIAS LODDENKEMPER, QUESTIONS EDITOR
    CHAPTER 18 Hippocampal Sclerosis and Dual Pathology 245
    OLESYA GRINENKO • INGMAR BLÜMCKE • IMAD M. NAJM
    CHAPTER 19 Malformations of Cortical Development and Epilepsy 252
    RICHARD J. LEVENTER • RENZO GUERRINI
    CHAPTER 20 New Neuropathologic Concepts in Focal Cortical Dysplasias 263
    HARVEY B. SARNAT
    CHAPTER 21 Brain Tumors and Epilepsy 272
    LARA JEHI • INGMAR BLÜMCKE
    CHAPTER 22 Posttraumatic Epilepsy 284
    JAY R. GAVVALA • STEPHAN U. SCHUELE
    CHAPTER 23 Epilepsy in the Setting of Cerebrovascular Disease 298
    CHARLES ÁKOS SZABÓ • STEPHEN HANTUS • BERND POHLMANN-EDEN
    CHAPTER 24 Epilepsy in the Setting of Neurocutaneous Syndromes 306
    PHILLIP L. PEARL • AJAY GUPTA
    CHAPTER 25 Epilepsy in the Setting of Inherited Metabolic and Mitochondrial Disorders 317
    SUMIT PARIKH • DOUGLAS R. NORDLI JR • DARRYL C. DE VIVO
    CHAPTER 26 Progressive Myoclonic Epilepsies 344
    BERND A. NEUBAUER • ANDREAS HAHN
    CHAPTER 27 Central Nervous System Infections and Epilepsy 359
    GAGANDEEP SINGH • J. M. K. MURTHY
    CHAPTER 28 Autoimmune Epilepsy and Encephalitis 369
    CLAUDE STERIADE • NICOLAS GASPARD • AHSAN N. V. MOOSA
    CHAPTER 29 Rasmussen Encephalitis 380
    CHRISTIAN G. BIEN • FRANÇOIS DUBEAU
    SECTION C ¦ DIAGNOSIS AND TREATMENT OF SEIZURES IN SPECIAL CLINICAL SETTINGS
    HOWARD P . GOODKIN, ASSOCIATE EDITOR • TOBIAS LODDENKEMPER, QUESTIONS EDITOR
    CHAPTER 30 Febrile Seizures and Genetic Epilepsy with Febrile Seizures Plus (GEFS+) 392
    SYNDI A. SEINFELD • MICHAEL DUCHOWNY
    CHAPTER 31 Approach to the Patient with a First Seizure 398
    EMILY L. JOHNSON • GREGORY K. BERGEY
    CHAPTER 32 Neonatal Seizures and EEG 404
    COURTNEY J. WUSTHOFF • ELI M. MIZRAHI • ROBERT R. CLANCY • ELIA M. PESTANA KNIGHT
    CHAPTER 33 Epilepsy in the Elderly 421
    ANDREY S. STOJIC • CAMILO I. GARCÍA GRACIA • LARA JEHI • ILO E. LEPPIK
    CHAPTER 34 Seizures Associated with Nonneurologic Medical Conditions 430
    STEPHAN EISENSCHENK • SWAPNA SURABHI • YUE WANGCHAPTER 35 Sleep and Epilepsy 439
    NANCY FOLDVARY-SCHAEFER • SILVIA NEME-MERCANTE
    CHAPTER 36 Status Epilepticus 449
    VINEET PUNIA • HOWARD P . GOODKIN
    CHAPTER 37 Electroencephalography and Seizures in the Intensive Care Setting 464
    STEPHEN HANTUS • NICHOLAS S. ABEND
    SECTION D ¦ DIFFERENTIAL DIAGNOSIS OF EPILEPSY
    LARA JEHI, ASSOCIATE EDITOR, QUESTIONS EDITOR
    CHAPTER 38 Psychogenic Nonepileptic Seizures 473
    W. CURT LAFRANCE JR • HAMADA HAMID ALTALIB • BECKY BIKAT TILAHUN
    CHAPTER 39 Other Nonepileptic Paroxysmal Disorders 483
    ELIA M. PESTANA KNIGHT • ADRIANA S. TANNER
    PART IV ¦ ANTISEIZURE MEDICATIONS
    SECTION A ¦ GENERAL PRINCIPLES OF ANTISEIZURE MEDICATION THERAPY
    BARRY E. GIDAL, ASSOCIATE EDITOR
    CHAPTER 40 Antiseizure Medication Development and Experimental Models 503
    MELISSA BARKER-HALISKI • H. STEVE WHITE
    CHAPTER 41 Mechanisms of Action of Antiseizure Medication 509
    MICHAEL A. ROGAWSKI • JOSÉ E. CAVAZOS
    CHAPTER 42 Pharmacokinetics and Drug Interactions 520
    GAIL D. ANDERSON
    CHAPTER 43 Initiation and Discontinuation of Antiseizure Medications 531
    VARDA GROSS-TSUR • RUTH C. SHINNAR • SHLOMO SHINNAR
    CHAPTER 44 Treatment of Acute and Repetitive Seizures 544
    IVÁN SÁNCHEZ FERNÁNDEZ • TOBIAS LODDENKEMPER
    CHAPTER 45 Hormones, Catamenial Epilepsy, Sexual Function, and Reproductive and Bone Health in Epilepsy 553
    NITIN K. SETHI • CYNTHIA L. HARDEN
    CHAPTER 46 Treatment of Epilepsy During Pregnancy 561
    PAGE B. PENNELL • P . EMANUELA VOINESCU
    CHAPTER 47 Individual Approach to Laboratory Monitoring of Antiseizure Medication 569
    SVEIN I. JOHANNESSEN • PHILIP N. PATSALOS
    SECTION B ¦ SPECIFIC ANTIEPILEPTIC MEDICATIONS AND TREATMENTS
    BARRY E. GIDAL, ASSOCIATE EDITOR
    CHAPTER 48 Benzodiazepines 575
    L. JOHN GREENFIELD JR • KINSHUK SAHAYA • SANG-HUN LEE
    CHAPTER 49 Carbamazepine, Oxcarbazepine, and Eslicarbazepine 599
    CARLOS A. M. GUERREIRO • MARILISA M. GUERREIRO • SCOTT MINTZER
    CHAPTER 50 Ethosuximide 610
    ANDRES M. KANNER • RAMSES RIBOT
    CHAPTER 51 Felbamate 623
    MONICA B. DHAKAR • EDWARD FAUGHT
    CHAPTER 52 Gabapentin and Pregabalin 629
    PIERO PERUCCACHAPTER 53 Lacosamide 641
    ROBERT T. WECHSLER • RAJ D. SHETH
    CHAPTER 54 Lamotrigine 646
    JOHN M. STERN • BARRY E. GIDAL
    CHAPTER 55 Levetiracetam and Brivaracetam 654
    ERIN M. OKAZAKI • JOSEPH I. SIRVEN • KATHERINE H. NOE • MATTHEW T. HOERTH • PAVEL KLEIN
    CHAPTER 56 Perampanel 663
    GREGORY L. KRAUSS • BARRY E. GIDAL
    CHAPTER 57 Phenobarbital and Primidone 669
    JACQUELYN L. BAINBRIDGE • MARK C. SPITZ • PEI SHIEEN WONG • SARAH N. FISCHER
    CHAPTER 58 Phenytoin and Fosphenytoin 678
    JEANNINE M. CONWAY
    CHAPTER 59 Rufinamide 693
    GREGORY L. KRAUSS • RAMA MAGANTI
    CHAPTER 60 Topiramate 701
    WILLIAM E. ROSENFELD
    CHAPTER 61 Valproate 715
    ANGELA K. BIRNBAUM • SUSAN E. MARINO
    CHAPTER 62 Vigabatrin 724
    KELLY G. KNUPP • ELIZABETH A. THIELE
    CHAPTER 63 Zonisamide 731
    TIMOTHY E. WELTY
    CHAPTER 64 Adrenocorticotropin and Steroids 738
    CRISTINA GO • O. CARTER SNEAD III
    CHAPTER 65 Cannabidiol 747
    JERZY P . SZAFLARSKI • ORRIN DEVINSKY
    CHAPTER 66 Antiseizure Medications in Clinical Development 752
    DEANA M. GAZZOLA • NORMAN DELANTY • JACQUELINE A. FRENCH
    CHAPTER 67 Less Commonly Used Antiseizure Medications 763
    ROBERT J. KOTLOSKI • ROBERT T. WECHSLER • BASIM M. UTHMAN • BAILEY G. SALIMES
    CHAPTER 68 Dietary Therapies for Epilepsy 772
    ERIC H. W. KOSSOFF
    PART V ¦ EPILEPSY SURGERY
    SECTION A ¦ IDENTIFYING SURGICAL CANDIDATES AND DEFINING THE EPILEPTOGENIC NETWORK
    LARA JEHI, ASSOCIATE EDITOR, QUESTIONS EDITOR
    CHAPTER 69 Issues of Medical Intractability for Surgical Candidacy 780
    SAMUEL WIEBE • CHURL-SU KWON • NATHALIE JETTÉ
    CHAPTER 70 Magnetic Resonance Imaging in the Evaluation for Epilepsy Surgery 788
    AHSAN N. V. MOOSA • PAUL M. RUGGIERI
    CHAPTER 71 Video–EEG Monitoring in the Presurgical Evaluation 806
    JEFFREY W. BRITTON • DAVID B. BURKHOLDER
    CHAPTER 72 Nuclear Imaging (PET, SPECT) 820
    WILLIAM DAVIS GAILLARDCHAPTER 73 Magnetoencephalography 831
    RICHARD C. BURGESS • JOHN C. MOSHER
    CHAPTER 74 MRI Postprocessing Techniques and Clinical Applications 849
    ZHONG IRENE WANG • STEPHEN E. JONES • ANDREA BERNASCONI
    CHAPTER 75 MRI Connectivity Analyses: Imaging Networks in Epilepsy 860
    EZEQUIEL GLEICHGERRCHT • LEONARDO BONILHA
    CHAPTER 76 Diffusion Tensor Imaging (DTI) and EEG-Correlated fMRI 867
    BEATE DIEHL • LOUIS LEMIEUX
    CHAPTER 77 Mapping Epileptic Networks with Intracranial Electrodes 881
    JUAN C. BULACIO • JORGE A. GONZÁLEZ-MARTÍNEZ
    SECTION B ¦ MAPPING ELOQUENT CORTEX
    LARA JEHI, ASSOCIATE EDITOR, QUESTIONS EDITOR
    CHAPTER 78 Functional Mapping with Neurophysiologic Techniques 891
    RIKI MATSUMOTO • SASHA DIONISIO • MARTIN STAUDT • JUAN C. BULACIO • DILEEP NAIR
    CHAPTER 79 Language and Memory Mapping 905
    JEFFREY R. BINDER • CHAD CARLSON
    SECTION C ¦ EPILEPSY SURGERY IN SPECIFIC CLINICAL SETTINGS
    TOBIAS LODDENKEMPER, ASSOCIATE EDITOR, QUESTIONS EDITOR
    CHAPTER 80 Surgery for Medically Refractory Temporal Lobe Epilepsy 917
    ALVIN Y. CHAN • WILLIAM E. BINGAMAN • IMAD M. NAJM • SUMEET VADERA
    CHAPTER 81 Surgery for Focal Cortical Dysplasias (FCDs) 924
    ANDRE PALMINI • IMAD M. NAJM • WILLIAM E. BINGAMAN
    CHAPTER 82 Hemispherectomy: Indications, Procedures, and Outcome 934
    AHSAN N. V. MOOSA • JORGE A. GONZÁLEZ-MARTÍNEZ • WILLIAM E. BINGAMAN
    CHAPTER 83 Surgical Approach in Multilesional or Multilobar Epilepsies 945
    ELIA M. PESTANA KNIGHT • ELAINE WYLLIE
    CHAPTER 84 Surgical Approach in Nonlesional Cases 954
    DEEPAK K. LACHHWANI • JORGE A. GONZÁLEZ-MARTÍNEZ
    CHAPTER 85 Hypothalamic Hamartoma 964
    JOHN F. KERRIGAN • ANGUS A. WILFONG
    CHAPTER 86 Corpus Callosotomy and Multiple Subpial Transection 982
    MICHAEL C. SMITH • RICHARD W. BYRNE • ANDRES M. KANNER
    CHAPTER 87 Epilepsy Surgery: Special Considerations in Children 991
    AHSAN N. V. MOOSA • ELAINE WYLLIE
    CHAPTER 88 Ablative Treatments for Epilepsy 1001
    PATRICK J. KARAS • A. BASIT KHAN • DANIEL J. CURRY
    CHAPTER 89 Outcome and Complications of Epilepsy Surgery 1012
    ROBERT A. MCGOVERN • LARA JEHI • JORGE A. GONZÁLEZ-MARTÍNEZ • WILLIAM E. BINGAMAN
    CHAPTER 90 Vagus Nerve Stimulation Therapy 1027
    JAMES W. WHELESS • ANDREW J. GIENAPP • BASANAGOUD MUDIGOUDAR
    CHAPTER 91 Responsive Neurostimulation Therapy: RNS System 1043
    CHRISTIANNE N. HECK • WILLIAM O. TATUM
    CHAPTER 92 Deep Brain Stimulation Epilepsy 1048
    ROBERT S. FISHERPART VI ¦ PSYCHOSOCIAL IMPACT, QUALITY OF LIFE, AND COMORBIDITIES, AND ECONOMICS OF EPILEPSY
    LARA JEHI, ASSOCIATE EDITOR, QUESTIONS EDITOR
    CHAPTER 93 Cognitive Effects of Epilepsy and Its Treatments 1058
    KIMFORD J. MEADOR
    CHAPTER 94 Psychiatric Comorbidity of Epilepsy 1064
    BETH A. LEEMAN-MARKOWSKI • STEVEN C. SCHACHTER
    CHAPTER 95 Sudden Unexpected Death in Epilepsy (SUDEP) 1078
    DAVID P . HARRIS • LISA M. BATEMAN
    CHAPTER 96 Driving and Social Issues in Epilepsy 1085
    AMY Z. CREPEAU • JOSEPH F. DRAZKOWSKI
    CHAPTER 97 Ambulatory Seizure Monitoring and Acute Seizure Detection 1092
    STEVEN C. SCHACHTER
    CHAPTER 98 Quality of Life with Epilepsy 1095
    TATIANA FALCONE • JESSICA R. FESLER
    APPENDIX ¦ ASSOCIATE EDITOR: BARRY E. GIDAL
    Indications for Antiseizure Medications Sanctioned by the U.S. Food and Drug Administration 1101
    BRITANY WALLS
    Index 1103
    • Features considerable new or significantly revised content reflecting the most current evidence-based treatment options.
    • Offers an in-depth review of all aspects of epileptology, including neuroimaging; epilepsy surgery; antiseizure medications; principles of electroencephalography; psychosocial impact, quality of life, and comorbidities; economics of epilepsy; and more.
    • Provides more than 500 CME-eligible review questions online, highlighting key concepts for the ABPN subspecialty exam and clinical practice.

    ​Enrich Your Ebook Reading Experience

    • Read directly on your preferred device(s),such as computer, tablet, or smartphone.
    • Easily convert to audiobook,powering your content with natural language text-to-speech. 
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Wyllie's Treatment of Epilepsy

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