VitalSource e-Book for Principles and Practice of Lung Cancer

Preface
Contributors
Color Figures

SECTION 1 Lung Cancer Epidemiology
1 The Etiology and Epidemiology of Lung Cancer
David Schottenfeld
2 The Tobacco Epidemic
Carolyn Dresler
3 Nontobacco-Related Lung Carcinogenesis
Tze-Ming Benson Chen, Ware G. Kuschner
4 Genetic Susceptibility to Lung Cancer
Christopher I. Amos, Joan E. Bailey-Wilson

SECTION 2 Lung Cancer Biology
5 An Overview of the Molecular Biology of Lung Cancer
Jill E. Larsen, Monica Spinola, Adi F. Gazdar, John D. Minna
6 Genomic Alterations in Lung Cancer
Marileila Varella Garcia
7 Epigenetic Changes in Lung Cancer: Pathobiological and Clinical Aspects
Ite A. Laird-Offringa
8 Molecular Events Surrounding the Angiogenic Switch of Lung Cancer
Jair Bar, Amir Onn, Roy S. Herbs
9 Applications of Proteomics to the Management of Lung Cancer
Pierre P. Massion, David P. Carbone
10 Molecular Prognostication of Lung Cancer
Betty C. Tong, David H. Harpole, Jr.
11 Examining the Cancer Stem Cell Hypothesis in Human Lung Cancers
Kerstin W. Sinkevicius, Stephen J. Curtis, Carla F. Kim
12 Lung Cancer and Its Microenvironment
Marie Wislez, Jacques Cadranel, Jonathan M. Kurie
13 Mouse Models of Lung Cancer
Ambra Pozzi
14 Cell Cycle and Vascular Targets for Radiotherapy
Luigi Moretti, Sebahat Ocak, Dennis E. Hallahan, Bo Lu, Misun Hwang

SECTION 3 Screening and Prevention
15 Population-Based Lung Cancer Prevention: An Overview
Anthony W. Kim, Mark A. Yoder, Michael J. Liptay, James L. Mulshine
16 Screening for Lung Cancer
Claudia I. Henschke, David F. Yankelevitz, Olli S. Miettinen
17 Low-Dose Computed Tomography Screening: Experiences from the Randomized Population-Based
Nelson Screening Trial
Rob J. van Klaveren, Harry J. de Koning
18 Fine-Needle Aspiration Cytology of Benign and Malignant Tumors of the Lung
Anjali Saqi, Madeline F. Vazquez
19 Early Detection of Lung Cancer Using Bronchoscopy
Annette McWilliams, Stephen Lam
20 Evolving Early Detection Modalities in Lung Cancer Screening
Simon D. Spivack, William Rom
21 Molecular Carcinogenesis and Chemoprevention of Lung Cancer
Fadlo Khuri, Nico Van Zandwijk

SECTION 4 Pathology
22 Molecular and Cellular Pathology of Lung Cancer
Wilbur A. Franklin, Masayuki Noguchi, Adriana Gonzalez

SECTION 5 Presentation, Diagnosis, and Staging
23 Clinical Presentation of Non–Small Cell Carcinoma of the Lung
Antoinette J. Wozniak, Shirish M. Gadgeel
24 Clinical Presentation of Small Cell Lung Cancer
Gregory A. Masters
25 Gender-Related Differences in Lung Cancer
Silvia Novello, Julie R. Brahmer, Laura P. Stabile, Jill M. Siegfried
26 Conventional Imaging of Non–Small Cell Lung Cancer
Leslie E. Quint, Naama R. Bogot, Sheila C. Rankin
27 Positron Emission Tomography in Lung Cancer
Johan Vansteenkiste, Christophe Dooms, Sigrid Stroobants
28 Bronchoscopy in the Diagnosis and Evaluation of Lung Cancer
Thomas G. Sutedja, Thomas Santo, Michael Zervos, Felix J.F. Herth
29 Surgical Evaluation of the Mediastinum
Frank C. Detterbeck
30 The International Staging System for Lung Cancer
Peter Goldstraw

SECTION 6 Surgical Management of Lung Cancer
31 Minimally Invasive Techniques for the Management of Lung Cancer
Robert J. McKenna, Jr.
32 Extent of Resection for Stage I Lung Cancer
Paul C. Lee, Nasser K. Altorki
33 Management of Ground-Glass Opacity Lesions
Hisao Asamura
34 Management of Stage II Non–Small Cell Lung Cancer and Pancoast Tumors
Matthew Steliga, Ashish Patel, Ara Vaporciyan
35 Vertebral Body Resection
Linda W. Martin, Garrett L. Walsh
36 Surgical Management of Second Primary and Metastatic Lung Cancer
Yvonne M. Carter, Dan J. Raz, David M. Jablons
37 Percutaneous Therapeutic Technologies for Medically Inoperable Lung Cancer
Shawn Haji-Momenian, Ricardo S. Santos, Hiran C. Fernando, Damian E. Dupuy
38 Surgical Management of Small Cell Lung Cancer
Theolyn Price, Francis Nichols
39 Complications of Surgery for Lung Cancer
Traves D. Crabtree, Chadrick E. Denlinger

SECTION 7 Radiation Therapy and Lung Cancer
40 Physical Basis of Modern Radiotherapy: Dose and Volume
Paul Keall, José Belderbos, Feng-Ming (Spring) Kong
41 Biological Basis of Fractionation and Timing of Radiotherapy
Dirk De Ruysscher, Vincent S. Khoo, Søren M. Bentzen
42 Radiotherapy for Locally Advanced Lung Cancer: Stages IIIA and IIIB
Jason R. Pantarotto, Suresh Senan
43 Stereotactic Techniques for Lung Cancer Treatment
Robert D. Timmerman, Timothy D. Solberg, Brian D. Kavanagh, Simon S. Lo
44 Radiation Treatment–Related Lung Damage
Zhongxing Liao, Elizabeth L. Travis, Ritsuko Komaki

SECTION 8 Chemotherapy and Lung Cancer
45 Chemotherapy for Advanced Non–Small Cell Lung Cancer
Leora Horn, Cesare Gridelli, Corey Langer, David H. Johnson
46 Chemotherapy for Recurrent or Refractory Advanced Non–Small Cell Lung Cancer
Peter M. Ellis, Frances A. Shepherd
47 Pharmacogenomics in Lung Cancer: Predictive Biomarkers for Chemotherapy
Oliver Gautschi, Philip C. Mack, David R. Gandara, Rafael Rosell

SECTION 9 Novel Targeted Agents and Lung Cancer
48 Antiangiogenic Agents
Christian Manegold, Leora Horn, Alan Sandler
49 Anti-EGFR Therapies: How to Select Patients
Fred R. Hirsch, Tetsuya Mitsudomi, Pasi A. Jänne
50 Other Signal Transduction Agents
Alex A. Adjei
51 Lung Cancer Vaccines
Nevin Murray, Robert Eager, John Nemunaitis
52 Targeted Therapies and Radiation in Lung Cancer
David Raben, Amanda Schwer, Paul Van Houtte

SECTION 10 Adjuvant and Neoadjuvant Approaches for Non–Small Cell Lung Cancer
53 Adjuvant Chemotherapy in Completely Resected Non–Small Cell Lung Cancer
Giorgio V. Scagliotti, Everett E. Vokes
54 Preoperative Chemotherapy for Early Stage Non–Small Cell Lung Cancer
Jan P. van Meerbeeck, Katherine M. Pisters
55 Preoperative Chemotherapy/Radiation Therapy for Early Stage and Locally Advanced Non–Small Cell Lung Carcinoma
Brian E. Lally, Harvey I. Pass, Kathy S. Albain
56 Stage IIIB Non–Small Cell Lung Cancer
Wilfried E.E. Eberhardt, Paul E. Van Schil, Walter Curran, Jr., Mark A. Socinski
57 Prophylactic Cranial Irradiation in Non–Small Cell Lung Cancer
Elizabeth Gore

SECTION 11 Treatment of Small Cell Lung Cancer
58 Chemotherapy for Small Cell Lung Cancer
Chao H. Huang, Frances A. Shepherd, Karen Kelly
59 Multimodality Therapy for Limited-Stage Small Cell Lung Cancer: Combining Chemotherapy and Radiotherapy
Sara Erridge, Nevin Murray, Andrew T. Turrisi III
60 Prophylactic Cranial Irradiation in Small Cell Lung Cancer
Cécile Le Péchoux, Aaron H. Wolfson

SECTION 12 Lung Cancer Emergencies
61 Endoscopic Ablational Therapies and Stenting
Michael Zervos, Costas Bizekis
62 Management of Malignant Pleural Effusion
Jessica S. Donington
63 Management of Overt Central Nervous System Metastases: Brain and Spinal Cord
Young Kwok, Roy A. Patchell, William F. Regine

SECTION 13 Other Thoracic Malignancies
64 Thymoma and Thymic Carcinoma
Patrick J. Loehrer, Sr., John Henley, Kenneth Kesler
65 Malignant Mesothelioma
Bruce W.S. Robinson, Paul Baas, Hedy Lee Kindler
66 Management of Mediastinal Tumors Not of Thymic Origin
Naveed Alam, Raja Flores
67 The Spectrum of Carcinoid Tumors
Paris A. Kosmidis

Index