The Gleason Grading System: A Complete Guide for Pathologists and Clinicians provides exhaustive coverage of the updated Gleason Grading System, which deals not only with pathology but also with the associated clinical correlations and prognosis. The Gleason Grading System is the most important prognostic marker of prostate cancer, which is critical to patient management and drives therapies across all disciplines dealing with prostate cancer. In addition to an extensive number of photographs, this book discusses in detail clinically related issues that are crucial for the urologist, radiotherapist, and oncologist to know, such as predicting upgrading and downgrading from needle biopsy to radical prostatectomy, risk of Gleason grading change over time, significance of tertiary grade patterns, and prognosis and implications related to various Gleason scores and different therapies. Images that were particularly difficult for contributing pathologists sent in for consultation are used in addition to classic examples, as these cases are the most informative in showing the difficulties with Gleason grading. This book is a valuable tool not only for surgical pathologists from the resident level to seasoned practitioners but also for urology residents, urologists, medical oncologists, and radiation oncologists.
ISBN/ISSN
9781469828121
Product Format
Vitalsource Fixed Layout eBook
Trim Size
8.375 x 10.875
Pages
224
Publication Date
March 15, 2013
Jonathan I. Epstein
Professor of Pathology, Urology and Oncology The Reinhard Professor of Urological Pathology Director of Surgical Pathology The Johns Hopkins Medical Institutions Baltimore, MD
Preface 1 Historical Evolution of the Gleason Grading System: From 1967 to the Contemporary Era 2 The Current Modified Gleason Grading System—Histologic Features of Conventional Prostate Adenocarcinoma 3 Grading Variants of Prostate Carcinoma 4 Principles of Gleason Grading in Current Practice and Comparison of Original and Modified Gleason Grading System 5 Grading Accuracy 6 Relation of Gleason Grade to Treatment
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