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The Bethesda Handbook of Clinical Hematology

Edition: 5
9781975211837
ISBN/ISSN:
9781975211837
Publication Date:
February 5, 2024
2024-02-5
9781975211837
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Written by national recognized experts and senior fellows at leading research institutions, including the National Institutes of Health, and edited ...
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  • Written by national recognized experts and senior fellows at leading research institutions, including the National Institutes of Health, and edited by Drs. Griffin P. Rodgers and Neal S. Young, The Bethesda Handbook of Clinical Hematology, 5th Edition, is a concise, comprehensive handbook designed for everyday clinical use. Organized in a quick-reference, portable format, it covers the clinical information you need to know for the diagnosis and treatment all of blood and bone marrow disorders. Readable and practical, the Bethesda Handbook features numerous tables, algorithms, illustrations, and bulleted lists throughout to help bridge the gap between cutting-edge science and everyday clinical practice.
    • Provides clinically focused, authoritative, and current guidance in this complex area, logically organized by disease category
    • Discusses the pathophysiology, natural history, risk factors, diagnosis, management, and follow-up of common hematological diseases
    • Features new diagnostic and treatment strategies, updated references, and revised information throughout
    • An ideal resource for practitioners at every level of training: students, residents, and fellows on a hematology or oncology service, as well as internists, hospitalists, family practitioners, pediatricians, and nurse practitioners whose practice includes patients with blood diseases
  • Edition
    5
    ISBN/ISSN
    9781975211837
    Product Format
    Paperback Book
    Pages
    560
    Edition
    5
    Publication Date
    February 5, 2024
    Weight
    1.6
  • GRIFFIN RODGERS
    NEAL STUART YOUNG
  • ix
    Pr eface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vi
    Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii
    Chapter 1 ¦ ir on Defi ciency . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
    Xing Fan and David J. Young
    Chapter 2 ¦ Defi ciencies of Vitamin b
    12
    and Folate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
    Arun S. Shet and Griffi n P . Rodgers
    Chapter 3 ¦ Hemol ytic Anemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
    Dina S. Parekh and Swee Lay Th ein
    Chapter 4 ¦ sickle Cell Anemia and thalassemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
    Matthew M. Hsieh, John F. Tisdale, and Griffi n P . Rodgers
    Chapter 5 ¦ P orph yrias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64
    Zhubin Gahvari and Peiman Hematti
    Chapter 6 ¦ bone Marrow Failure syndromes: Aplastic Anemia, Acquired and
    Constitutional; Paroxysmal nocturnal Hemoglobinuria; Pure red blood Cell Aplasia; and
    Agran ulocytosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
    Rebecca Bystrom and Bhavisha Patel
    Chapter 7 ¦ My elodysplastic syndr omes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95
    Jibran Durrani, Katherine R. Calvo, and Emma M. Groarke
    Chapter 8 ¦ the Myeloproliferative neoplasms: Polycythemia Vera, essential
    thrombocythemia, Primary Myelofi brosis, and Chronic Myelomonocytic Leukemia . . . . . . . . 119
    M a tt h e w J . O ln es
    Chapter 9 ¦ neutrophil Disorders and neutropenias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136
    Matthew M. Hsieh and Harry L. Malech
    Chapter 10 ¦ Childhood Hematologic Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147
    Christopher C. Denton and Alan S. Wayne
    Chapter 11 ¦ Acute Myeloid Leukemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165
    Rebecca Bystrom and Christopher S. Hourigan
    Chapter 12 ¦ Acute Lymphoblastic Leukemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186
    Eric Nickels, Deepa Bhojwani, and Alan S. Wayne
    Chapter 13 ¦ Chronic Myelogenous Leukemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200
    Agnes S. M. Yong and A. John Barrett
    Chapter 14 ¦ Chronic Lymphocytic Leukemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218
    Andy Itsara, Emily Tomasulo, Adrian Wiestner, and Clare Sun
    Chapter 15 ¦ Hodgkin L ymphoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236
    Disha Dalela and Mark Roschewski
    Chapter 16 ¦ non-Hodgkin L ymphomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249
    R ic h a r d F . L i tt le
    C ON T E N TS x Contents
    Chapter 17 ¦ Multiple Myeloma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276
    eha Korde, Sham Mailankody, and Saad Z. Usmani
    Chapter 18 ¦ Hematopoietic stem Cell t ransplantation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294
    mie Y. Hur and Richard W . Childs
    Chapter 19 ¦ thrombocytopenia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319
    Sandhya R. Panch and Cynthia E. Dunbar
    Chapter 20 ¦ Disorders of Hemostasis i: Coagulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340
    Meaghan Colling
    Chapter 21 ¦ Disorders of Hemostasis ii . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 354
    Meaghan Colling
    Chapter 22 ¦ V enous thromboembolism . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 370
    edro E. Alcedo and Christopher Pleyer
    Chapter 23 ¦ Consultations in Anticoagulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386
    edro E. Alcedo and W . Keith Hoots
    Chapter 24 ¦ blood t ransfusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 401
    mes O. Long and Kathleen (Cathy) Conry-Cantilena
    Chapter 25 ¦ Hemochromatosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 438
    inda H. Song, David Daniel, and Susan F. Leitman
    Chapter 26 ¦ Consultative Hematology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 455
    ing Fan, Pierre Noel, Charles Bolan, and Arielle L. Langer
    Chapter 27 ¦ interpretation of standard Hematologic tests . . . . . . . . . . . . . . . . . . . . . . . . . . 477
    Disha Dalela, Katherine R. Calvo, and Vid Leko
    Chapter 28 ¦ basic Principles and Clinical Applications of Flow Cytometry . . . . . . . . . . . . . . 502
    aul C. Braylan, Thomas A. Fleisher, and Constance M. Yuan
    ndex . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521
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