iv 
   Contents  
     Digital Contents: Quizzes, Animations and Videos List  x   
    Contributors  xii    
    Preface  xvi    
    SECTION I: BASIC CONCEPTS    
      CHAPTER 1 CARDIAC ELECTRICAL ACTIVITY     1
    Tobin H. Lim and David G. Strauss  
    The Book:  Marriott’s Practical Electrocardiography , 13th Edition   2
    The Electrocardiogram   3
    Anatomic Orientation of the Heart   4
    The Cardiac Cycle   6
    Cardiac Impulse Formation and Conduction   10
    Recording Long-Axis (Base-Apex) Cardiac Electrical Activity   12
    Recording Short-Axis (Left Versus Right) Cardiac Electrical Activity   17
      CHAPTER 2 RECORDING THE ELECTROCARDIOGRAM     23
    David G. Strauss, Tobin H. Lim, and Douglas D. Schocken  
    The Standard 12-Lead Electrocardiogram   24
    Correct and Incorrect Electrode Placements   31
    Alternative Displays of the 12 Standard Electrocardiogram Leads   34
    Alternative Electrode Placement   40
    Other Practical Points for Recording the Electrocardiogram   41
      CHAPTER 3  INTERPRETATION OF THE NORMAL 
ELECTROCARDIOGRAM     45
    David G. Strauss, Tobin H. Lim, and Douglas D. Schocken  
    Electrocardiographic Features   46
    Rate and Regularity   48
    P-wave Morphology   50
    The PR Interval   51
    Morphology of the QRS Complex   52
    Morphology of the ST Segment   59
    T-wave Morphology   61
    U-wave Morphology   63
    QT and QTc Intervals   64   Contents v
    Cardiac Rhythm   65
    A Final Word   69
      
  
eChapter I: INTERPRETATION OF THE 
ELECTROCARDIOGRAM IN 3D    
    Charles W. Olson, E. Harvey Estes Jr, Vivian P. Kamphuis, 
Esben Andreas Carlsen, David G. Strauss, and Galen S. Wagner (deceased)  
    SECTION II: CHAMBER ENLARGEMENT AND 
CONDUCTION ABNORMALITIES    
      CHAPTER 4 CHAMBER ENLARGEMENT     73
    Douglas D. Schocken, Ljuba Bacharova, and David G. Strauss  
    Atrial Enlargement   75
    Electrocardiogram Pattern With Atrial Enlargement   78
    Ventricular Enlargement   80
    Electrocardiogram QRS Changes With Ventricular Enlargement   82
    Left-Ventricular Dilation   83
    Left-Ventricular Hypertrophy   85
    Electrocardiogram Pattern With Left-Ventricular Hypertrophy   86
    Right-Ventricular Hypertrophy   90
    Biventricular Hypertrophy   95
    Scoring Systems for Assessing LVH and RVH   97
      CHAPTER 5  INTRAVENTRICULAR CONDUCTION 
ABNORMALITIES     101
    David G. Strauss and Tobin H. Lim  
    Normal Conduction   102
    Bundle-Branch and Fascicular Blocks   103
    Unifascicular Blocks   107
    Bifascicular Blocks   115
    Systematic Approach to the Analysis of Bundle-Branch and 
Fascicular Blocks   124
    Clinical Perspective on Intraventricular-Conduction Disturbances   127
    SECTION III: ISCHEMIA AND INFARCTION    
      CHAPTER 6  INTRODUCTION TO MYOCARDIAL ISCHEMIA 
AND INFARCTION     135
    David G. Strauss, Douglas D. Schocken, and Tobin H. Lim  
    Introduction to Ischemia and Infarction   136
    Electrocardiographic Changes   140 vi Contents
      CHAPTER 7  SUBENDOCARDIAL ISCHEMIA FROM 
INCREASED MYOCARDIAL DEMAND     149
    David G. Strauss and Tobin H. Lim  
    Changes in the ST Segment   150
      CHAPTER 8  TRANSMURAL MYOCARDIAL ISCHEMIA 
FROM INSUFFICIENT BLOOD SUPPLY     163
    David G. Strauss and Tobin H. Lim  
    Changes in the ST Segment   164
    Changes in the T Wave   175
    Changes in the QRS Complex   176
       
 
 TRANSMURAL MYOCARDIAL ISCHEMIA 
FROM INSUFFICIENT BLOOD SUPPLY: 
ONLINE SUPPLEMENT     
    David G. Strauss and Tobin H. Lim  
    Estimating Extent, Acuteness, and Severity of Ischemia   
      CHAPTER 9 MYOCARDIAL INFARCTION     181
    David G. Strauss and Tobin H. Lim  
    Infarcting Phase   182
    Chronic Phase   189
       
  
MYOCARDIAL INFARCTION: 
ONLINE SUPPLEMENT    
    David G. Strauss and Tobin H. Lim  
    Estimating Infarct Size and Infarcts in the Presence of 
Conduction Abnormalities   
    Myocardial Infarction and Scar in the Presence of 
Conduction Abnormalities   
    SECTION IV: DRUGS, ELECTROLYTES, AND 
MISCELLANEOUS CONDITIONS    
      CHAPTER 10 ELECTROLYTES AND DRUGS     203
    Robbert Zusterzeel, Jose Vicente Ruiz, and David G. Strauss  
    Cardiac Action Potential   204
    Electrolyte Abnormalities   206
    Drug Effects   212
      CHAPTER 11 MISCELLANEOUS CONDITIONS     223
    Douglas D. Schocken, Tobin H. Lim, and David G. Strauss  
    Introduction   224
    Cardiomyopathies   224   Contents vii
    Pericardial Abnormalities   228
    Pulmonary Abnormalities   232
    Intracranial Hemorrhage   237
    Endocrine and Metabolic Abnormalities   238
      CHAPTER 12 CONGENITAL HEART DISEASE     245
    Sarah A. Goldstein and Richard A. Krasuski  
    Atrial Septal Defects   246
    Ventricular Septal Defect   251
    Patent Ductus Arteriosus   253
    Pulmonary Stenosis   253
    Aortic Stenosis   253
    Coarctation of the Aorta   253
    Tetralogy of Fallot   254
    Ebstein Anomaly   255
    Congenitally Corrected Transposition of the Great Arteries   256
    Complete Transposition of the Great Arteries   257
    Fontan Circulation   258
    SECTION V: ABNORMAL RHYTHMS    
      CHAPTER 13 INTRODUCTION TO ARRHYTHMIAS     263
    Zak Loring, David G. Strauss, Douglas D. Schocken, 
and James P. Daubert  
    Introduction to Arrhythmia Diagnosis   264
    Problems of Automaticity   265
    Problems of Impulse Conduction: Reentry   268
    Approach to Arrhythmia Diagnosis   272
    Clinical Methods for Detecting Arrhythmias   280
    Ambulatory Electrocardiogram Monitoring   281
    Invasive Methods of Recording the Electrocardiogram   286
      CHAPTER 14 PREMATURE BEATS     293
    James P. Daubert, Aimée Elise Hiltbold, and Fredrik Holmqvist  
    Premature Beat Terminology   294
    Differential Diagnosis of Wide Premature Beats   297
    Mechanisms of Production of Premature Beats   298
    Atrial Premature Beats   299
    Junctional Premature Beats   304
    Ventricular Premature Beats   307
    Right-Ventricular Versus Left-Ventricular Premature Beats   312
    Multiform Ventricular Premature Beats   315
    Groups of Ventricular Premature Beats   316
    Vulnerable Period and R-on-T Phenomenon   317
    Prognostic Implications of Ventricular Premature Beats   317viii Contents
      CHAPTER 15 SUPRAVENTRICULAR TACHYARRHYTHMIAS     321
    Kevin P. Jackson and James P. Daubert  
    Introduction   322
    Differential Diagnosis of Supraventricular Tachycardia   324
    Sinus Tachycardia   329
    Atrial Tachycardia   331
    Junctional Tachycardia   334
    Atrioventricular Nodal Reentrant Tachycardia   335
    Accessory Pathway Mediated Tachycardia   338
      CHAPTER 16 ATRIAL FIBRILLATION AND FLUTTER     345
    Jonathan P. Piccini, James P. Daubert, and Tristram D. Bahnson  
    Pathophysiology of Atrial Fibrillation and Atrial Flutter   346
    Twelve-Lead Electrocardiographic Characteristics of Atrial Fibrillation   350
    Atrial Flutter   355
    Twelve-Lead Electrocardiographic Characteristics of 
Atypical Atrial Flutter   358
    Clinical Considerations of Atrial Fibrillation and Atrial Flutter   364
      CHAPTER 17 VENTRICULAR ARRHYTHMIAS     369
    Albert Y. Sun and Jason Koontz  
    Definitions of Ventricular Arrhythmias   370
    Etiologies and Mechanisms   370
    Diagnosis   371
      CHAPTER 18 BRADYARRHYTHMIAS     391
    Larry R. Jackson II, Camille Genise Frazier-Mills, Francis E. Ugowe, 
and James P. Daubert  
    Mechanisms of Bradyarrhythmias: Decreased Automaticity   393
    Atrioventricular Conduction Disease   400
    Severity of Atrioventricular Block   400
    Location of Atrioventricular Block   410
    Atrioventricular Nodal Block   411
    Infranodal (Purkinje) Block   414
      CHAPTER 19 VENTRICULAR PREEXCITATION     421
    Donald D. Hegland, Stephen Gaeta, and James P. Daubert  
    Clinical Perspective   423
    Pathophysiology   426
    Electrocardiographic Diagnosis of Ventricular Preexcitation   430
    Ventricular Preexcitation as a “Great Mimic” of Other 
Cardiac Problems   434
    Electrocardiographic Localization of the Pathway of 
Ventricular Preexcitation   435
    Ablation of Accessory Pathways   438   Contents ix
      CHAPTER 20 INHERITED ARRHYTHMIA DISORDERS     445
    John Symons and Albert Y. Sun  
    The Long QT Syndrome (LQTS)   446
    LQTS Electrocardiographic Characteristics   446
    Electrocardiogram as Used in Diagnosis for LQTS   448
    The Short QT Syndrome (SQTS)   449
    SQTS Electrocardiographic Characteristics   449
    Electrocardiogram as Used in Diagnosis for SQTS   451
    The Brugada Syndrome   452
    Arrhythmogenic Right-Ventricular Cardiomyopathy/Dysplasia   454
    J-wave Syndrome   458
    Catecholaminergic Polymorphic Ventricular Tachycardia   460
      CHAPTER 21 IMPLANTABLE CARDIAC PACEMAKERS     465
    Brett D. Atwater and Daniel J. Friedman  
    Basic Concepts of the Implantable Cardiac Pacemaker   466
    Pacemaker Modes and Dual-Chamber Pacing   472
    Pacemaker Evaluation   478
    Myocardial Location of the Pacing Electrodes   482
    Special Algorithms to Avoid Right-Ventricular Pacing   484
    Cardiac Resynchronization Therapy       485
Index    493