Atlas of Gastrointestinal Pathology
A Pattern-Based Approach to Non-Neoplastic Biopsies
Edition:
2
9781975218294
Publication Date:
November 11, 2024
2024-11-11
9781975218294
Closely mirroring the daily sign-out process, Atlas of Gastrointestinal Pathology: A Pattern-Based Approach to Non-Neoplastic Biopsies, 2nd Edition, by Drs. ...
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Product Description
Closely mirroring the daily sign-out process,
Atlas of Gastrointestinal Pathology: A Pattern-Based Approach to Non-Neoplastic Biopsies, 2nd Edition , by Drs. Maryam Pezhouh and Meredith Pittman, is a highly illustrated, efficient guide to accurate diagnosis. This practical reference uses a proven, pattern-based approach to clearly explain how to interpret challenging cases by highlighting red flags in the clinical chart and locating hidden clues in the slides. Useful as a daily “scope-side guide,” it features numerous clinical and educational features that help you find pertinent information, reach a correct diagnosis, and assemble a thorough and streamlined pathology report.
A companion volume for
Atlas of Gastrointestinal Pathology is also available and focuses on neoplastic conditions.
More than 1,000 high-quality, full-color images illustrate the full morphologic spectrum of the major patterns of non-neoplastic GI tract pathology, providing abundant and varied examples of each diagnosis. Each image is captioned with key diagnostic considerations and includes callouts showing subtle features and diagnostic clues. Practical tools throughout the text include: Tables that emphasize salient clinicopathologic features, management implications, and therapeutic options Checklists for key elements of the diagnostic approach and sample notes for inclusion in pathology reports Brief reviews of normal histology that provide contrast to succeeding patterns “Pearls and Pitfalls” and “Near Misses” sections with lessons from real life sign-out experience “Frequently Asked Questions” sections that discuss common diagnostic dilemmas “Sample Note” sections that offer a template of how to sign out cases from the simple to the complex Comprehensive quizzes that provide experience with high-yield, board-style teaching topics Enrich your eBook reading experience
Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.
Specs
Edition
2
ISBN/ISSN
9781975218294
Product Format
Hardcover Book
Trim Size
8 3/8 x 10 7/8
Pages
496
Table
25
Edition
2
Publication Date
November 11, 2024
Weight
3.25
Maryam Kherad Pezhouh Meredith Pittman
Table of contents
CONTENTS 1 ESOPHAGUS ..................................................................................................1 The Unremarkable Esophagus .......................................................................2 Acute Esophagitis Pattern ..............................................................................7 Gastroesophageal reflux disease ........................................................................ 7 Infections ........................................................................................................... 10 Medications ....................................................................................................... 19 Other (malignancy, amyloidosis, radiation injury, and vasculitis) ....................... 30 Eosinophilic Pattern ......................................................................................32 Eosinophilic esophagitis (EoE) ........................................................................... 33 Gastroesophageal reflux disease ...................................................................... 37 Drug reaction ..................................................................................................... 38 Allergy ............................................................................................................... 38 Photodynamic therapy ...................................................................................... 39 Systemic collagen vascular disorders (scleroderma) .......................................... 40 Parakeratotic Pattern ....................................................................................40 Gastroesophageal reflux disease ...................................................................... 41 Candida ............................................................................................................. 42 Leukoplakia pattern/epidermoid metaplasia .................................................... 44 Esophagitis dissecans superficialis/sloughing esophagitis ................................ 46 Esophageal Lymphocytosis Pattern..............................................................49 Gastroesophageal reflux disease ...................................................................... 50 Crohn disease .................................................................................................... 50 Contact mucositis .............................................................................................. 52 Candida ............................................................................................................. 52 Common variable immunodeficiency ................................................................ 52 Dysmotility disorders ......................................................................................... 53 Lichen planus/“lichenoid” pattern .................................................................... 53 Graft-versus-host disease .................................................................................. 56 Pigments .......................................................................................................59 Near Misses ..................................................................................................59 Gastric inlet patch/heterotopic gastric mucosa ................................................. 59 Pancreatic heterotopia/metaplasia .................................................................... 60 Glycogenic acanthosis ....................................................................................... 62 Squamous papilloma ......................................................................................... 65 Multilayered epithelium ..................................................................................... 67 Amyloid ............................................................................................................. 68 Granular cell tumor ............................................................................................ 69 Granulomata ...................................................................................................... 71 Apoptotic body prominence ............................................................................. 72 Ring mitoses (taxol and colchicine) ................................................................... 73 Malignancy ........................................................................................................ 74 Appendix ......................................................................................................74 1% Alcian blue, pH 2.5 Recipe .......................................................................... 74 PAS/AB pH 2.5 Recipe ...................................................................................... 74 2 STOMACH ....................................................................................................81 The Unremarkable Stomach .........................................................................82 Layers ................................................................................................................ 82 Histology and function ...................................................................................... 83 Reactive Gastropathy Pattern ......................................................................87Acute Gastritis Pattern .................................................................................92 Medications ....................................................................................................... 92 Infections ........................................................................................................... 94 Focally enhanced gastritis ............................................................................... 106 Chronic Gastritis Pattern ............................................................................108 Autoimmune metaplastic atrophic gastritis ..................................................... 108 Environmental metaplastic atrophic gastritis ................................................... 112 A patterns-based approach to chronic gastritis .............................................. 112 Lymphocytic Gastritis Pattern.....................................................................122 Collagenous Gastritis Pattern.....................................................................128 Gastric Eosinophilia Pattern .......................................................................130 Idiopathic eosinophilic gastritis ....................................................................... 132 Medications ..................................................................................................... 132 Parasitic infection............................................................................................. 134 Inflammatory bowel disease ............................................................................ 134 Connective tissue disorder and vasculitis ........................................................ 135 Neoplasia ........................................................................................................ 135 Hyperplasia Pattern ....................................................................................136 Oxyntic gland hyperplasia ............................................................................... 137 Foveolar hyperplasia ....................................................................................... 143 Granulomatous Gastritis Pattern ................................................................148 Vascular and Hemorrhagic Changes Pattern ..............................................151 Portal hypertensive gastropathy ...................................................................... 152 Gastric antral vascular ectasia.......................................................................... 153 Doxycycline-induced injury.............................................................................. 155 Amyloid ........................................................................................................... 156 Radiation gastritis pattern ............................................................................... 156 Pigments and Extras ...................................................................................158 Iron .................................................................................................................. 158 Gastric pseudomelanosis ................................................................................ 161 Calcinosis ......................................................................................................... 162 Resins .............................................................................................................. 164 90 Yttrium-labeled microspheres ....................................................................... 164 Near Misses ................................................................................................166 Amyloidosis ..................................................................................................... 166 Apoptotic body prominence ........................................................................... 167 Poorly differentiated adenocarcinoma with signet ring cell features .............. 167 Russell body gastritis ....................................................................................... 169 Mucous neck cells ........................................................................................... 170 Sarcina ............................................................................................................. 170 Bezoar and other foreign material ................................................................... 171 Mast cell disease ............................................................................................. 172 3 SMALL BOWEL ...........................................................................................185 The Unremarkable Small Bowel .................................................................186 Acute Duodenitis Pattern ...........................................................................195 Peptic injury ..................................................................................................... 196 Infection ........................................................................................................... 197 Inflammatory bowel disease ............................................................................ 199 Immunoglobulin A (IgA) vasculitis ................................................................... 200 Acute Ileitis Pattern ....................................................................................201 Medications ..................................................................................................... 202 Inflammatory bowel disease ............................................................................ 203 Chronic Inflammation Pattern .................................................................... 207 Crypt Architectural Disturbance Pattern ....................................................209 Inflammatory bowel disease ............................................................................ 210 Diaphragm disease .......................................................................................... 212Graft-versus-host disease ................................................................................ 219 Medications ..................................................................................................... 222 Allograft rejection, small bowel ....................................................................... 223 Radiation enteritis ............................................................................................ 226 Pouchitis and pouch-related changes ............................................................. 227 Eosinophilia Pattern ...................................................................................234 Malabsorption Pattern ...............................................................................236 Overview of malabsorption patterns ............................................................... 236 Medications ..................................................................................................... 238 Reactive duodenopathy .................................................................................. 239 Small intestinal bacterial overgrowth .............................................................. 241 Gluten-sensitive enteropathy (celiac disease) ................................................. 244 Nongluten protein sensitivity .......................................................................... 252 Tropical sprue .................................................................................................. 253 Common variable immunodeficiency .............................................................. 255 Inflammatory bowel disease ............................................................................ 256 Autoimmune enteropathy ............................................................................... 257 Collagenous enteritis ....................................................................................... 259 Foamy Macrophage Pattern .......................................................................261 Mycobacterium avium complex ...................................................................... 262 Whipple disease .............................................................................................. 264 Nonspecific scattered macrophages ............................................................... 269 Dilated Lacteal Pattern ...............................................................................270 Primary lymphangiectasia ................................................................................ 270 Secondary lymphangiectasia ........................................................................... 271 Metaplasia and Heterotopia.......................................................................274 Reactive duodenopathy .................................................................................. 274 Gastric heterotopia .......................................................................................... 276 Pancreatic heterotopia .................................................................................... 277 Pyloric metaplasia ............................................................................................ 278 Pigments and Extras ...................................................................................280 Titanium (“peyer patch pigment”) .................................................................. 281 Tattoo pigment ................................................................................................ 282 Pseudomelanosis duodeni .............................................................................. 283 Formalin pigment (acid formaldehyde hematin) ............................................. 285 Melanoma ........................................................................................................ 286 90 Yttrium-labeled microspheres ....................................................................... 287 Near Misses ................................................................................................290 Sneaky adenocarcinoma .................................................................................. 290 Isospora ........................................................................................................... 291 Giardia duodenalis (giardia lamblia or giardia intestinalis) .............................. 294 Common variable immunodeficiency .............................................................. 295 Collagenous enteritis ....................................................................................... 296 Sneaky neuroendocrine tumor ........................................................................ 297 4 COLON .......................................................................................................309 The Unremarkable Colon ...........................................................................310 Focal Active Colitis Pattern ........................................................................314 Acute self-limited colitis .................................................................................. 316 Acute Colitis Pattern ..................................................................................316 Cytomegalovirus.............................................................................................. 317 Salmonella ....................................................................................................... 319 Shigella ............................................................................................................ 321 Campylobacter ................................................................................................ 322 Ischemic Colitis Pattern ..............................................................................323 Ischemia ........................................................................................................... 324 Infection (Escherichia coli 0157:H7 and Clostridioides difficile) ...................... 329Pseudomembranous Pattern ......................................................................332 Chronic Colitis Pattern ...............................................................................335 A three-step approach to the chronic colitis pattern....................................... 336 Inflammatory bowel disease ............................................................................ 343 Curable inflammatory bowel disease mimics .................................................. 353 Diverticular disease ......................................................................................... 354 Diversion-associated colitis ............................................................................. 358 Sexually transmitted infectious colitis .............................................................. 361 Cord colitis syndrome ...................................................................................... 365 Immune check point inhibitor colitis ............................................................... 366 Resins .............................................................................................................. 370 Lymphocytic Pattern ...................................................................................370 Lymphocytic colitis .......................................................................................... 371 Collagenous colitis .......................................................................................... 373 Medications ..................................................................................................... 376 Eosinophilia Pattern ...................................................................................376 Idiopathic eosinophilic colitis .......................................................................... 377 Inflammatory bowel disease ............................................................................ 378 Allergy ............................................................................................................. 378 Medications ..................................................................................................... 379 Infection ........................................................................................................... 380 Collagen vascular disorder and vasculitis ........................................................ 381 Granulomatous Pattern ..............................................................................383 Apoptotic colopathy pattern ........................................................................... 387 Pigments and Extras ...................................................................................389 Melanosis coli (also referred to as pseudomelanosis coli) ............................... 389 Tattoo pigment ................................................................................................ 392 Air artifact and intramucosal lipoma ................................................................ 393 Pneumatosis cystoides intestinalis ................................................................... 396 Muciphages ..................................................................................................... 398 Resins .............................................................................................................. 399 Near Misses ................................................................................................400 Endometriosis .................................................................................................. 400 Benign signet ring cell change ........................................................................ 401 Pulse granulomata ........................................................................................... 402 Lifting agents granulomata.............................................................................. 404 Spirochetosis ................................................................................................... 405 APPENDIX A .....................................................................................................415 APPENDIX B .....................................................................................................451 INDEX ...............................................................................................................471
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9781975218294
Atlas of Gastrointestinal Pathology
9781975218294
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