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Werner & Ingbar's The Thyroid

A Fundamental and Clinical Text
9781451120639
ISBN/ISSN
9781451120639
Publication Date
October 8, 2012
2012-10-8
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  • Description
    Werner & Ingbar’s The Thyroid: A Fundamental and Clinical Text, 10th Edition has been extensively revised and streamlined to deliver the most comprehensive coverage of the thyroid including anatomy, development, biochemistry, physiology, pathophysiology, and treatment of all thyroid disorders. Entirely new chapters on the surgical management of thyroid cancer, thyroid disruptors, and thyroid hormone analogs are in this edition. New authors and an international group of contributors elevate this classic text that includes extensive clinical coverage of thyroid dysfunction’s effects on other organ systems. Also addressed are clinical controversies regarding the ageing thyroid, subclinical hypothyroidism and hyperthyroidism and thyroid disease in pregnancy.
    New to this edition:
    · Twenty-three chapters authored by new contributors and international experts
    · A companion website with fully searchable text for quick reference
    · Three new chapters discuss surgical management of thyroid cancer, thyroid disruptors, and thyroid hormone analogs to keep you up-to-date on the latest advances in the field
    “This is an update of the classic thyroid text and is clearly essential for endocrinologists and thyroid surgeons. It is certainly useful for those undertaking thyroid related research but it is clearly far too detailed for students other than those undertaking basic science research in the thyroid. This edition has added the surgical management of thyroid disorders which is clearly an asset for the endocrine surgeon. With this type of reference text it is inevitable that there will be information from many years ago cited. There has however been a clear effort to update information and expand detail including more up-to-date references — studies related to markers of disease progression in thyroid cancer, cytopathology of thyroid cancer. Studies and other works that are references are of high quality and in general integral to the subject matter being discussed. There has also been a clear effort made to critically appraise the texts being cited. In general it is well written. Sections of the book can be a little monotonous only due to the subject matter i.e. thyroid hormone synthesis and thyroglobulin structure, function and biosynthesis. The diagrams and illustrations particularly in the basic science section are very useful. The use of colour images would have made them a lot more pleasing on the eye. Only for those subspecializing in thyroid disorders or conducting research into the thyroid gland. This book has helped me to understand the thyroid gland further and will continue to do so. It is the type of book one consults to answer a specific question and to provide context for a clinical problem.” — BMA Medical Book Award reviewer, 2013 BMA Medical Book Awards
  • Specs
    Edition
    10
    ISBN/ISSN
    9781451120639
    Product Format
    HC-Printed Cover
    Trim Size
    8.375 x 10.875
    Pages
    912
    Illustration
    345
    Edition
    10
    Publication Date
    October 8, 2012
    Weight
    5.45
  • Lewis E. Braverman MD
    Professor of Medicine, Boston University School of Medicine; Chief, Section of Endocrinology, Diabetes, and Nutrition, Department of Medicine, Boston Medical Center, Boston, MA
    David Cooper
    University of New South Wales, Sydney, Australia
  • Features
    New to this edition:
    · Twenty-three chapters authored by new contributors and international experts
    · A companion website with fully searchable text for quick reference
    · Three new chapters discuss surgical management of thyroid cancer, thyroid disruptors, and thyroid hormone analogs to keep you up-to-date on the latest advances in the field
  • Table of contents
    SECTION I. THE NORMAL THYROID
    '
    PART A. HISTORY, DEVELOPMENT, ANATOMY

    Chapter 1 The Heritage of the Thyroid: A Brief History
    Clark T. Sawin

    Chapter 2 Development of the Hypothalamic–Pituitary–Thyroid Axis
    Pilar Santisteban

    Chapter 3 Anatomy and Pathology of the Thyrotrophs
    Fabio Rotondo, Kalman Kovacs, and Eva Horvath

    PART B.B>THYROID HORMONE SYNTHESIS AND SECRETION

    Chapter 4A Thyroid Hormone Synthesis: Thyroid Iodide Transport
    Nancy Carrasco

    Chapter 4B Thyroid Hormone Synthesis
    Peter Kopp

    Chapter 5 Thyroglobulin Structure, Function, and Biosynthesis
    Héctor M. Targovnik

    PART C.B>PERIPHERAL THYROID HORMONE BINDING AND METABOLISM

    Chapter 6 Thyroid Hormone Transport Proteins and the Physiology of Hormone Binding
    Salvatore Benvenga

    Chapter 7 Intracellular Pathways of Iodothyronine Metabolism/Implications of Deiodination for Thyroid Hormone Action
    Antonio C. Bianco and Brian W. Kim

    PART D.B>THYROID HORMONE ACTION

    Chapter 8 Genomic and Nongenomic Actions of Thyroid Hormones
    Paul M. Yen and Gregory A. Brent

    Chapter 9 Thyroid Hormone Structure–Function Relationships
    Stephen D. Ayers, John D. Baxter, and Paul Webb

    PART E.B>FACTORS THAT CONTROL THYROID FUNCTION

    Chapter 10A Chemistry and Biosynthesis of Thyrotropin
    Ronald N. Cohen and Fredric E. Wondisford

    Chapter 10B The Thyrotropin Receptor
    Gilbert Vassart

    Chapter 10C Regulation of Thyrotropin Secretion
    Anthony N. Hollenberg

    Chapter 11A Age Related Changes in Thyroid Function
    Laura Boucai and Martin I. Surks

    Chapter 11B Effects of Drugs on TSH Secretion, Thyroid Hormones Absorption, Synthesis, Metabolism, and Action
    S´ebastien Thalmann and Christoph A. Meier

    Chapter 11C Nonthyroidal Illness Syndrome
    Wilmar M. Wiersinga and Greet Van den Berghe

    Chapter 11D Iodine Deficiency and Endemic Cretinism
    Michael Zimmerman

    Chapter 11E Effect of Excess Iodide: Clinical Aspects
    Elio Roti and Apostolos G. Vagenakis

    SECTION II.ASSESSMENT OF THYROID STRUCTURE AND FUNCTION

    Chapter 12 Thyroid Radionuclide Uptake and Imaging Studies
    Richard L. Wahl

    Chapter 13A Measuring Serum Thyroid–Stimulating Hormone, Thyroid Hormones, Thyroid-Directed Antibodies, and Transport Proteins
    Offie P. Soldin

    Chapter 13B Measurement of Thyroglobulin
    Carole Ann Spencer

    Chapter 14 Nonisotopic Techniques of Thyroid Imaging
    Laszlo Hegedu¨ s and Finn Noe Bennedbaek

    Chapter 15 Physical Examination of the Thyroid Gland
    James V. Hennessey

    Chapter 16 Pathology and Cytopathology
    Zubair Wahid Baloch and Virginia A LiVolsi

    SECTION III.THYROID DISEASES: THYROTOXICOSIS

    Chapter 17 Introduction to Thyrotoxicosis
    Lewis E. Braverman and David S. Cooper

    PART A.B>CAUSES OF THYROTOXICOSIS

    Chapter 18A Pathogenesis of Graves’ Disease
    Terry F. Davies

    Chapter 18B Ophthalmopathy
    Petros Perros and Jane Dickinson

    Chapter 18C Thyroid Dermopathy and Thyroid Acropachy
    Vahab Fatourechi

    Chapter 19 Thyrotropin-Induced Thyrotoxicosis
    Paolo Beck-Peccoz and Luca Persani

    Chapter 20 Toxic Adenoma and Toxic Multinodular Goiter
    Ralf Paschke

    Chapter 21 Trophoblastic Tumors
    Jerome M. Hershman

    Chapter 22 Sporadic Painless, Painful Subacute and Acute Infectious Thyroiditis
    Alan P. Farwell

    Chapter 23 Thyrotoxicosis of Extrathyroid Origin
    Angela M. Leung and Joshua D. Safer

    PART B.B>ORGAN SYSTEM MANIFESTATIONS

    Chapter 24 Overview of the Clinical Manifestations of Thyrotoxicosis
    Henry B. Burch

    Chapter 25 The Cardiovascular System in Thyrotoxicosis
    Irwin Klein and Sara Danzi

    Chapter 26 Thyroid Hormones in Thermogenesis, Intermediary Metabolism, and Obesity
    Thomas Reinehr

    Chapter 27 The Male and Female Reproductive System in Thyrotoxicosis
    Gerasimos E. Krassas and Nikolaos Pontikides

    Chapter 28 The Skeletal System in Thyrotoxicosis
    Graham R. Williams

    Chapter 29 Behavioral and Psychiatric Aspects of Thyrotoxicosis
    Michael Bauer, Mary Samuels, and Peter C. Whybrow

    Chapter 30 Thyrotoxic Storm
    Leonard Wartofsky

    PART C.B>DIAGNOSIS AND MANAGEMENT OF THYROTOXICOSIS

    Chapter 31 Diagnosis of Thyrotoxicosis
    Paul W. Ladenson

    Chapter 32 Treatment of Thyrotoxicosis
    David S. Cooper

    Chapter 33 Subclinical Thyrotoxicosis
    Douglas S. Ross

    SECTION IV. THYROID DISEASES: HYPOTHYROIDISM

    Chapter 34 Introduction to Hypothyroidism
    Lewis E. Braverman and David S. Cooper

    PART A. CAUSES OF HYPOTHYROIDISM

    Chapter 35 Chronic Autoimmune Thyroiditis
    Anthony P. Weetman

    Chapter 36 Genetic Defects Causing Hypothyroidism
    Thomas Vulsma and Jan J.M. de Vijlder

    Chapter 37 Primary Hypothyroidism Due to Other Causes
    Peter A. Singer

    Chapter 38 Central Hypothyroidism
    Luca Persani and Paolo Beck-Peccoz

    PART B.B>ORGAN SYSTEM MANIFESTATIONS OF HYPOTHYROIDISM

    Chapter 39 Overview of the Clinical Manifestations of Hypothyroidism
    Michael T. McDermott

    Chapter 40 The Cardiovascular System in Hypothyroidism
    Irwin Klein and Sara Danzi

    Chapter 41 The Male and Female Reproductive System in Hypothyroidism
    Gerasimos E. Krassas and Nikolaos Pontikides

    Chapter 42 The Skeletal System in Hypothyroidism
    Graham R. Williams

    Chapter 43 Psychiatric and Cognitive Effects of Hypothyroidism
    Kathryn G. Schuff, Mary H. Samuels, Peter C. Whybrow, and Michael Bauer

    Chapter 44 Myxedema Coma
    Leonard Wartofsky

    PART C. MANAGEMENT OF HYPOTHYROIDISM

    Chapter 45 Diagnosis of Hypothyroidism
    Paul W. Ladenson

    Chapter 46 Treatment of Hypothyroidism
    Jacqueline Jonklaas

    Chapter 47 Subclinical Hypothyroidism
    Douglas Ross

    SECTION V.THYROID DISEASES: NONTOXIC DIFFUSE AND MULTINODULAR GOITER

    Chapter 48 Multinodular Goiter: Pathogenesis and Management
    Hans Graf

    Chapter 49 Clinical Evaluation and Management of Thyroid Nodules
    Susan J. Mandel, Jill E. Langer, and Michael M. Kaplan

    SECTION VI . THYROID CANCERS

    Chapter 50A Carcinomas of Follicular Epithelium: Epidemiology and Pathogenesis
    Arthur B. Schneider and Alina V. Brenner

    Chapter 50B Molecular Genetics of Tumors of Thyroid Follicular Cells
    James A. Fagin and Yuri Efimovich Nikiforov

    Chapter 50C Carcinoma of the Follicular Epithelium: Surgical Therapy
    Gregory W. Randolph and Gerard M. Doherty

    Chapter 50D Staging and Prognosis of Differentiated Thyroid Cancer
    Richard Kloos

    Chapter 50E Medical Management of Differentiated Epithelial Cell Thyroid Cancer
    Sebastiano Filetti, R. Michael Tuttle, and Steven I. Sherman

    Chapter 51 Medullary Thyroid Carcinoma
    Mimi I. Hu, Camilo Jimenez, Gilbert J. Cote, and Robert F. Gagel

    Chapter 52 Anaplastic Thyroid Cancer and Miscellaneous Tumors of the Thyroid
    Joshua P. Klopper, Madeleine A. Kane, and Bryan R. Haugen

    SECTION VII.THE THYROID IN INFANCY AND CHILDHOOD

    Chapter 53 The Maturation of Thyroid Function in the Perinatal Period and During Childhood
    Delbert A. Fisher and Rosalind S. Brown

    Chapter 54A Hypothyroidism in Infants and Children:Neonatal Screening
    Guy Van Vliet and Johnny Deladoey

    Chapter 54B Hypothyroidism in Infants and Children:
    Congenital Hypothyroidism
    Guy Van Vliet and Johnny Deladoey

    Chapter 54C Hypothyroidism in Infants, Children, and Adolescents: Acquired Hypothyroidism
    Guy Van Vliet and Johnny Deladoey

    Chapter 55 Hyperthyroidism in the Neonatal Period and Childhood
    Stephen H. LaFranchi and Cheryl E. Hanna

    SECTION VIII. SPECIAL TOPICS IN THYROIDOLOGY

    Chapter 56 Thyroid Disorders During Pregnancy and Postpartum
    John H. Lazarus and Jorge H. Mestman

    Chapter 57 Thyroid Disruptors
    Elizabeth N. Pearce

    Chapter 58 Reduced Sensitivity to Thyroid Hormone: Defects of Transport, Metabolism, and Action
    Alexandra M. Dumitrescu and Samuel Refetoff


  • Editorial Reviews
    “This is an update of the classic thyroid text and is clearly essential for endocrinologists and thyroid surgeons. It is certainly useful for those undertaking thyroid related research but it is clearly far too detailed for students other than those undertaking basic science research in the thyroid. This edition has added the surgical management of thyroid disorders which is clearly an asset for the endocrine surgeon. With this type of reference text it is inevitable that there will be information from many years ago cited. There has however been a clear effort to update information and expand detail including more up-to-date references — studies related to markers of disease progression in thyroid cancer, cytopathology of thyroid cancer. Studies and other works that are references are of high quality and in general integral to the subject matter being discussed. There has also been a clear effort made to critically appraise the texts being cited. In general it is well written. Sections of the book can be a little monotonous only due to the subject matter i.e. thyroid hormone synthesis and thyroglobulin structure, function and biosynthesis. The diagrams and illustrations particularly in the basic science section are very useful. The use of colour images would have made them a lot more pleasing on the eye. Only for those subspecializing in thyroid disorders or conducting research into the thyroid gland. This book has helped me to understand the thyroid gland further and will continue to do so. It is the type of book one consults to answer a specific question and to provide context for a clinical problem.” — BMA Medical Book Award reviewer, 2013 BMA Medical Book Awards
  • Review
  • Questions and Answers

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