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Publication Date
October 11, 2012
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  • Description
    The recent advances in many aspects of kidney diseases have mandated the ninth edition of Schrier's Diseases of the Kidney . This all-encompassing work provides both clinicians and academicians with information they need to treat and study kidney disorders. Combining basic and clinical sciences, the book provides authoritative, concise, and readily accessible information. About 200 international authorities, guided by a team of five distinguished authorities in nephrology, create an invaluable resource. Dr. Schrier, the long-time sole editor of this work, has recruited four eminent nephrologists as co-editors for this edition.
    The book is divided into eleven sections that cover:
    • Structural, Functional Correlations in the Kidney
    • Clinical Evaluation
    • Cystic and Tubular Disorders
    • Infections of the Urinary Tract and the Kidney
    • Acute Renal Injury
    • Hypertension
    • Glomerular, Interstitial, and Vascular Renal Diseases
    • Systemic Diseases of the Kidney
    • Disorders of Electrolyte, Water, and Acid-Base
    • Chronic Kidney Disease
    • Management of End-Stage Renal Disease
    • Content has been consolidated into two volumes
    Plus, with this new edition you have FREE online access to the companion website that contains fully searchable text and an image bank so you have access to the content anytime, anywhere.
  • Specs
    Product Format
    HC-Printed Cover
    Trim Size
    8.375 x 10.875
    Publication Date
    October 11, 2012
  • Robert W. Schrier MD

    Professor of Medicine
    Division of Renal Disease and Hypertension
    University of Colorado Health Sciences Center
    Aurora, CO

    Thomas M. Coffman MD
    James R. Clapp Professor of Medicine
    Chief, Division of Nephrology
    Duke University and Durham VA Medical Centers
    Durham, North Carolina
    Program Director in Cardiovascular and Metabolic Disorders
    Duke-NUS Graduate Medical School
    Ronald J. Falk MD
    Cardiology Section, Boston City Hospital, Boston, MA
    Bruce A. Molitoris MD
    Professor of Medicine
    Indiana University
    Roudebush VA Medical Center 
    Indianapolis, Indiana
    Eric G. Neilson MD
    Hugh Jackson Morgan Professor, Chairman, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
  • Table of contents
    Section I Structural and Functional Correlations in the Kidney

    1. Structural---Functional Relationships in the Kidney
    Robert F. Reilly Jr., Ruth Ellen Bulger, Astrid Weins, and Wilhelm Kriz

    2. Clinical Importance of Nephron Mass
    Valerie A. Luyckx and Thomas F. Mueller

    3. Renal Circulation and Glomerular Hemodynamics
    William J. Arendshorst and L. Gabriel Navar

    4. Regulation of Water Balance: Urine Concentration and Dilution
    Yumi Noda and Sei Sakaki

    5. Tubular Sodium Transport
    Arohan R. Subramanya, Núria M. Pastor-Solar, W. Brian Reeves, and Kenneth R. Hallows

    6. Tubular Potassium Transport
    David B. Mount

    7. Renal Acid---Base Transport
    Thomas D. DuBose Jr. and Amanda K. Goode

    8. Hormones and the Kidney
    Sola Aoun Bahous, Maya Khairallah, Joumana T. Chaiban, and Kamal F. Badr

    Section II Clinical Evaluation

    9. Laboratory Evaluation of Kidney Disease
    Lesley A. Inker, Richard A. Lafayette, Ashish Upadhyay, and Andrew S. Levey

    10. Ultrasonography and Nuclear Medicine
    Frederic Rahbari-Oskoui, Andrew T. Taylor, and William Charles O’Neill

    11. Computed Tomography and Magnetic Resonance Imaging
    Kyongtae Bae and Sonal Krishan

    12. Diagnostic Angiography and Therapeutic Endovascular Intervention of the Renal Circulation
    Alex Perino, Rajan Gupta, and Ivan P. Casserly

    13. Renal Biopsy: Indications and Evaluation
    I. David Weiner, C. Craig Tisher, and Byron P. Croker

    Section III Cystic and Tubular Disorders

    14. Introduction to Genetic Renal Disease
    Erum Hartung, Terry Watnick, and Gregory G. Germino

    15. Nephronophthisis-Medullary Cystic Kidney Disease
    Friedhelm Hildebrandt, Rannar Airik, and John A. Sayer

    16. Autosomal Dominant Polycystic Kidney Disease
    Stefan Somlo and Arlene B. Chapman

    17. Alport Syndrome, Fabry Disease, and Nail-Patella Syndrome
    Godela M. Brosnahan, Martin Gregory, Imed Halal, and Berenice Y. Reed

    18. Isolated Renal Tubular Disorders: Mechanisms and Clinical Expression
    Thomas D. DuBose Jr. and Amanda K. Goode

    19. Urinary Tract Obstruction and Reflux Nephropathy
    Ryan B. Pickens and Edward D. Kim

    20. Nephrolithiasis
    Keith A. Hruska and Anne M. Beck

    Section IV Infections of the Urinary Tract and the Kidney

    21. Host-Pathogen Interactions and Host Defense Mechanisms
    Keira Melican, Ferdinand X. Choong, and Agneta Richter-Dahlfors

    22. Cystitis and Urethritis
    Annelie Brauner and Milan Chromek

    23. Infections of the Upper Urinary Tract
    Lindsay E. Nicollé

    24. Renal and Perirenal Abscesses
    Neha D. Nanda and Louise M. Dembry

    25. Complicated Urinary Tract Infections
    Dennis J. Mikolich* and Stephen H. Zinner

    26. Fungal Infections of the Urinary Tract
    Carol A. Kauffman

    27. Urinary Tract Tuberculosis
    Mark S. Pasternack and Robert H. Rubin

    Section V Acute Kidney Injury

    28. Epidemiology, Diagnosis and Therapy of Acute Kidney Injury
    Etienne Macedo and Ravindra L. Mehta

    29. Pathophysiology of Ischemic Acute Kidney Injury
    Charles L. Edelstein and Robert W. Schrier

    30. Pathophysiology of Nephrotoxic Cell Injury
    Brian S. Cummings and Rick G. Schnellmann

    31. Antibiotic- and Immunosuppression-Related Renal Failure
    Marc E. De Broe

    32. Nephrotoxicity of Nonsteroidal Antiinflammatory Agents, Analgesics,
    and Inhibitors of the Renin-Angiotensin System
    Biff F. Palmer

    33. Contrast-Induced Acute Kidney Injury
    Steven D. Weisbord and Paul M. Palevsky

    34. Nephrotoxicity Secondary to Environmental Agents, Heavy Metals, Drug Abuse, and Lithium
    Veronica Torres da Costa e Silva, Etienne Macedo, and Luis Yu

    35. Acute Tubulointerstitial Nephritis
    Garabed Eknoyan and Rajeev Raghavan

    36. Acute Kidney Injury Associated with Pigmenturia or Crystal Deposits
    Abolfazl Zarjou and Anupam Agarwal

    37. Acute Kidney Injury Secondary to Tropical Hemorrhagic Viral Infections and Snakebite
    Emmanuel A. Burdmann

    38. Acute Kidney Injury Following Hematopoietic Cell Transplantation and Severe Burns
    Justin Belcher and Chirag R. Parikh

    Section VI Hypertension

    39. Role of the Kidneys in Hypertension
    Joey P. Granger and Eric M. George

    40. Hypertension in Chronic Kidney Disease
    Peter N. Van Buren and Robert D. Toto

    41. Hypertension in End-Stage Kidney Disease
    Rajiv Agarwal

    42. Renal Artery Stenosis, Renovascular Hypertension, and Ischemic Nephropathy
    Stephen C. Textor

    43. Hypertension Due to Primary Aldosteronism and Related Disorders
    Emmanuel L. Bravo, Muhammed A. Rafey, and Surafel F. Gebreselassie

    44. Malignant Hypertension and Other Hypertensive Crises
    Charles R. Nolan and Stuart L. Linas

    Section VII Glomerular, Interstitial, and Vascular Renal Diseases

    45. Mechanisms of Immune Glomerular Injury
    William G. Couser

    46. Acute Infectious Glomerulonephritis: Including Post-streptococcal and Other Bacterial Infection---Related Glomerulonephritis
    Laura L. Mulloy and Michael P. Madaio

    47. Viral Glomerulonephritis
    Warren Kupin

    48. Vasculitic Diseases of the Kidney
    Julieanne G. McGregor, Patrick H. Nachman, J. Charles Jennette, and Ronald J. Falk

    49. Immunoglobulin A Nephropathy and Henoch-Schönlein Purpura
    Jan Novak and Bruce A. Julian

    50. Membranoproliferative Glomerulonephritis and Dense Deposit Disease
    J. Ashley Jefferson, Miguel Palma-Diaz, and Charles E. Alpers

    51. Membranous Nephropathy
    Laurence Beck, Jr. and David Salant

    52. Nephrotic Syndrome and the Podocytopathies: Minimal Change Nephropathy, Focal Segmental Glomerulosclerosis, and Collapsing Glomerulopathy
    H. William Schnaper and Jeffrey B. Kopp

    53. Renal Involvement in Systemic Lupus Erythematosus
    Brad H. Rovin, Daniel J. Birmingham, and Tibor Nadasdy

    54. Systemic Sclerosis, Rheumatoid Arthritis, Sjögren Syndrome, and Polymyositis-Dermatomyositis
    Meryl Waldman, James E. Balow, and Howard A. Austin III

    55. Hemolytic-Uremic Syndrome, Thrombotic Thrombocytopenic Purpura, and Acute Cortical Necrosis
    Marina Noris, Giuseppe Remuzzi, and Piero Ruggenenti

    56. Renal Artery Thrombosis, Thromboembolism, Aneurysms, Atheroemboli and Renal Vein Thrombosis
    John W. O’Bell, George P. Bayliss, and Lance D. Dworkin

    57. Chronic Tubulointerstitial Nephritis
    Allison A. Eddy and Ikuyo Yamaguchi

    Section VIII Systemic Diseases of the Kidney

    58. Clinical Aspects of Diabetic Nephropathy
    Jamie P. Dwyer and Julia B. Lewis

    59. The Normal and Diseased Kidney in Pregnancy
    Michelle A. Hladunewich, Ayodele Odutayo, and Ravi Thadhani

    60. Monoclonal Gammopathies: Multiple Myeloma, Amyloidosis, and Related Disorders
    Pierre Ronco, Frank Bridoux, and Pierre Aucouturier

    61. Hyperuricemia, Gout, and the Kidney
    Duk-Hee Kang, Mehmet Kanbay, and Richard Johnson

    62. Sickle Cell Disease
    Vimal K. Derebail and Abhijit V. Kshirsagar

    63. Tropical Nephrology
    Rashad S. Barsoum, Tarek Fayad, Kearkiat Praditpornsilpa, and Visith Sitprija

    64. A Clinical Approach to Kidney Disease in Infants, Children, and Adolescents
    Craig B. Langman, Gal Finer, and Neziha Celebi

    65. Renal Function and Disease in the Aging Kidney
    Ramesh Saxena, Andrew Fenves, Xueqing Yu, Nosratola D. Vaziri, Fred G. Silva, and Xin J. Zhou

    Section IX Disorders of Electrolyte, Water, and Acid Base

    66. Mechanisms of Diuretic Action
    David H. Ellison, Ewout J. Hoorn, and Robert W. Schrier

    67. Cardiac Failure and the Kidney
    William T. Abraham and Robert W. Schrier

    68. Liver Disease and the Kidney
    Pere Ginès, Andrés Cárdenas, Elsa Solà, and Robert W. Schrier

    69. The Nephrotic Syndrome
    Jeroen K.J. Deegens, Robert W. Schrier, and Jack F.M. Wetzels

    70. The Syndrome of Inappropriate Antidiuretic Hormone Secretion and Other Hypoosmolar Disorders
    Joseph G. Verbalis

    71. Nephrogenic and Central Diabetes Insipidus
    Daniel G. Bichet

    72. Disorders of Potassium and Acid-Base Metabolism in Association with Renal Disease
    Mark A. Perazella and Asghar Rastegar

    73. Disorders of Phosphorus, Calcium, and Magnesium Metabolism
    Keith A. Hruska, Moshe Levi, and Eduardo Slatopolsky

    74. Fluid-Electrolyte and Acid-Base Disorders Complicating Diabetes Mellitus
    Horacio J. Adrogué and Nicolaos E. Madias

    Section X Chronic Kidney Disease

    75. Pathophysiology and Nephron Adaptation in Chronic Kidney Disease
    Radko Komers, Timothy W. Meyer, and Sharon Anderson

    76. Anemia in Chronic Kidney Disease
    James E. Novak and Jerry Yee

    77. Mineral and Bone Disorder in Chronic Kidney Disease
    Elvira O. Gosmanova and Darryl L. Quarles

    78. Nervous System Manifestations of Renal Disease
    Yeong-Hau Howard Lien

    79. Cardiac Disease in Chronic Kidney Disease
    Patrick S. Parfrey and Sean W. Murphy

    80. Metabolic and Endocrine Dysfunctions in Uremia
    Eberhard Ritz, Marcin Adamczak, and Andrzej Wiecek

    Section XI Management of End-Stage Renal Disease

    81. Immunobiology and Immunopharmacology of Renal Allograft Rejection
    Choli Hartono, Terry B. Strom, and Manikkam Suthanthiran

    82. Clinical Aspects of Renal Transplantation
    Alexander C. Wiseman, James E. Cooper, and Laurence Chan

    83. Peritoneal Dialysis
    Seth Furgeson, Rajnish Mahrotra, John M. Burkart, and Isaac Teitelbaum

    84. Hemodialysis
    Scott D. Bieber and Jonathan Himmelfarb

    85. Dietary Factors in the Treatment of Chronic Kidney Disease
    Sreedhar A. Mandayam, William E. Mitch, and Joel D. Kopple

    86. Use of Drugs in Patients with Renal Failure
    Ali J. Olyaei, Jessica L. Steffl, and William M. Bennett

  • Features
    All chapters have been updated, with particularly extensive changes to areas such as hereditary disease, acute renal failure, and hypertension
    Content has been consolidated into two volumes
    Expanded editorial team provides in-depth expertise in all areas of nephrology
    References available online link to Medline abstracts and to selected full-text articles
    Thousands of new references have been added, and obsolete references have been deleted
    Book provides information on basic sciences, laboratory diagnosis, and imaging keyed to the needs of clinicians
    Each section of the book is designed to be a self-contained "textbook" for an area of neprhology
  • Editorial Reviews
    " This is probably the most comprehensive work available on the diseases of the kidney. It is also an authoritative book, with the collective knowledge and insight of renowned international experts assembled within its pages. Yet it is concise and tightly organized, considering that medical information usually tends to be encyclopedic in nature, especially when looking at its many aspects. But most important of all, the information in this book is easily accessible. How so? First, by turning to the pages of the sections and chapters of this very well-organized book that we itemize below, you will easily find the topics you want to read on. Second, by going online and registering your copy (see instructions below) you can quickly locate what you’re looking for, and much more. As before, the ninth edition of this classic work has been put together to provide the most comprehensive and updated information for academic and practicing physicians to help care for their patients with kidney disease and hypertension. This massive two-volume book represents not only the work of the five editors...but in total over 200 physicians and other experts in various medical specialties. Most of the contributing authors of the 86 chapters in the eleven sections of this book are from the United States, but many are from 19 other countries, namely Belgium, Brazil, Canada, China, Egypt, France, Germany, India, Italy, Japan, Lebanon, Poland, South Korea, Spain, Sweden, Thailand, the Netherlands, Turkey, and United Kingdom. The best way for medical students, residents, and practitioners in nephrology to know the extent of the coverage of this book is to look at the titles of the eleven sections that comprise its contents, which we list below:
    1. Structural and Functional Correlations in the Kidney
    2. Clinical Evaluation
    3. Cystic and Tubular Disorders
    4. Infections of the Urinary Tract and the Kidney
    5. Acute Kidney Injury
    6. Hypertension
    7. Glomerular, Interstitial, and Vascular Renal Diseases
    8. Systemic Diseases of the Kidney
    9. Disorders of Electrolyte, Water, and Acid Base
    10. Chronic Kidney Disease
    11. Management of End-Stage Kidney Disease

    The entire contents of this book are accessible online and fully searchable. Other useful features are also available online that are not found in the book.
    There have been many medical developments in nephrology since the last – eighth – edition was published. This current edition was released to incorporate those advances in this medical specialty. The editors inform us that nephrology is a field that combines the basic and clinical sciences. They write that the primary goal of this ninth edition is to successfully integrate this knowledge. But they point out that the 11 sections of this text “can stand on their own.” To give you an overview of what you will find in the two volumes of this large book, the first section presents the structural, physiologic and biochemical aspects of the kidney. You will find the latest advances in molecular and cellular biology covered in it, with emphasis on the most current developments on cell imaging, ion channels, and receptors. The other 10 sections that follow provide material on the various diseases. Each section begins with a chapter on the pathophysiology of the particular disease or diseases covered. The editors have provided chapters within a section that present the various aspects of the subject of the section. This makes the coverage comprehensive. In turn, the choice and organization of materials within the chapters themselves serve to enhance the comprehensiveness of the entire book. As an example, let’s take a look at Section II entitled Clinical Evaluation , which contains five chapters: 9 through 13, that present different means of evaluating the condition of kidney:
    9. Laboratory Evaluation of Kidney Disease
    10. Ultrasonography and Nuclear Medicine
    11. Computed Tomography and Magnetic Resonance Imaging
    12. Diagnostic Angiography and Therapeutic Endovascular Intervention
    13. Renal Biopsy: Indications and Evaluation
    Another valuable feature of this book is the large number of graphics throughout the book. These facilitate and enhance learning and understanding of the subjects, topics, and subtopics covered in the various chapters. You will find numerous kinds of graphics including boxes, charts, diagrams, drawings, micrographs (including many through an electron microscope with fine details), schematics, tables, and other forms of presentation of information. Nephrology is a complicated medical specialty to study, with a lot of detailed information. So the editors have ensured to provide you with numerous materials for further study on any topic. They present long lists (in some instances, several pages long) of information sources in the References section at the end of each chapter. Among them are articles in journals, chapters in books, titles of books, as well as other valuable resources. This is a monumental work of immense benefit to those studying to practice in this field, as well as those already in it, to help patients with kidney diseases and disorders."
    Book Review by : Nano Khilnani, BizIndia, Online News, 10/5/2014
  • Review
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