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MR and CT Perfusion and Pharmacokinetic Imaging: Clinical Applications and Theoretical Principles

MR and CT Perfusion and Pharmacokinetic Imaging: Clinical Applications and Theoretical Principles

9781451147155
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9781451147155
Publication Date
May 3, 2016
2016-05-3
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9781451147155
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  • Description
    Essential reading for both clinicians and researchers, this comprehensive resource covers what you need to know about the basic principles of perfusion, as well as its many clinical applications.  Broad coverage outlines the overarching framework that interlinks methods such as DSC, DCE, CTP, and ASL.  International experts in the field demonstrate how perfusion and pharmacokinetic imaging can be effectively used to analyze medical conditions, helping you reach accurate diagnoses and monitor disease progression and response to therapy.
     
    Key Features
    • Provides thorough coverage of CT and MR perfusion, including clinical applications, in a single, convenient volume.
    • Covers every area relevant to perfusion: image acquisition and reconstruction methods, contrast agent based methods for measuring organ perfusion and pharmacokinetic modeling, x-ray dose and general safety considerations, the basic concepts of perfusion, the methods of acquiring perfusion data, models and formulas to compute relevant perfusion parameters, protocols and how to make studies comparable, patient setup, and more.
    • Contains “pearls” and clinical summaries throughout, helping you quickly grasp the most important points of each topic.
    • Places complex technical and mathematical material in separate boxes which can be referred to as needed.
    • Offers a basis for understanding potential future applications in the management of oncologic, cerebral, renal, pulmonary, and cardiac pathologies.
    Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:
    • Complete content with enhanced navigation
    • Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web
    • Cross-linked pages, references, and more for easy navigation
    • Highlighting tool for easier reference of key content throughout the text
    • Ability to take and share notes with friends and colleagues
    • Quick reference tabbing to save your favorite content for future use
  • Specs
    Edition
    1
    ISBN/ISSN
    9781451147155
    Product Format
    HC-Printed Cover
    Trim Size
    8.375 x 10.875
    Pages
    1296
    Table
    0
    Publication Date
    May 3, 2016
    Weight
    7.35
  • About The Author(s)
    Roland Bammer Ph.D
  • Features
    Key Features
    • Provides thorough coverage of CT and MR perfusion, including clinical applications, in a single, convenient volume.
    • Covers every area relevant to perfusion: image acquisition and reconstruction methods, contrast agent based methods for measuring organ perfusion and pharmacokinetic modeling, x-ray dose and general safety considerations, the basic concepts of perfusion, the methods of acquiring perfusion data, models and formulas to compute relevant perfusion parameters, protocols and how to make studies comparable, patient setup, and more.
    • Contains “pearls” and clinical summaries throughout, helping you quickly grasp the most important points of each topic.
    • Places complex technical and mathematical material in separate boxes which can be referred to as needed.
    • Offers a basis for understanding potential future applications in the management of oncologic, cerebral, renal, pulmonary, and cardiac pathologies.
    Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:
    • Complete content with enhanced navigation  
    • Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web
    • Cross-linked pages, references, and more for easy navigation
    • Highlighting tool for easier reference of key content throughout the text
    • Ability to take and share notes with friends and colleagues
    • Quick reference tabbing to save your favorite content for future use
  • Table of contents
    Part I: Theory
    Section 1: Instrumentation & Basics

    1 Primer on CT Physics and Hardware 
    Jiang Hsieh, Marc Kachelriess
    2 CT Image Reconstruction Basics
    Joachim Hornegger, Andreas Maier, Markus Kowarschik
    3 Dose Considerations in CT Perfusion
    Lifeng Yu, Shuai Leng, Lance J. Phillips, Dawn Banghart, Cynthia H. McCollough
    4 Clinical Applications and Theoretical Principles: Primer on Physics of MR and Hardware 
    Maxim Zaitsev, Michael Markl
    5 MR Image Reconstruction 
    Jeffrey Tsao, Vikas Gulani
    6 MR Relaxation Theory and Exchange Processes in the Presence of Contrast Agents 
    Joel R. Garbow, Joseph J.H. Ackerman
    7 MR and CT Contrast Agents for Perfusion Imaging and Regulatory Issues 
    Henrik S. Thomsen, Peter Dawson, Michael F. Tweedle
    8 Contrast Agent Safety and Nephrogenic Systemic Fibrosis 
    Moazzem Kazi, Georg Bongartz, Martin R. Prince

    Section 2: CT Perfusion Imaging
    9 Acquisition Schemes for Computed Tomography Perfusion 
    Roland Bammer
    10 Xe-Enhanced CT Perfusion Measurements 
    Andrew P. Carlson, Howard Yonas

    Section 3: Dynamic Susceptibility Contrast-Based PWI
    11 Susceptibility Contrast in Tissues: Gradient Echoes versus Spin Echoes 
    Jerrold L. Boxerman, Matthias J.P. van Osch, Kathleen M. Schmainda
    12 Magnetic Resonance Pulse Sequences for Dynamic Susceptibility Contrast 
    Eric Peterson, Alexey A. Samsonov, Johan van den Brink, Gary H. Glover, Shalini A. Amukotuwa, Heiko H. Schmiedeskamp, Rexford D. Newbould,
    Roland Bammer
    13 Vessel Size Imaging 
    Valerij G. Kiselev, Heiko H. Schmiedeskamp
    14 Oxygen Extraction Fraction (OEF) Imaging 
    Weili Lin, Hongyu An, Thomas Christen

    Section 4: Arterial Spin Labeling
    15 Basic Principles of Arterial Spin Labeling: Continuous versus Pulsed Arterial Spin Labeling 
    Yufen Chen, John A. Detre
    16 Readout and Background Suppression Techniques 
    David Thomas, Matthias Günther, Xavier Golay
    17 Pseudo-Continuous Arterial Spin Labeling 
    David C. Alsop, Ajit Shankaranarayanan
    18 Confounding Effects in Arterial Spin Labeling 
    Danny J.J. Wang, María A. Fernández-Seara, Hanzhang Lu
    19 Flow Territory Mapping: Region-Selective Arterial Spin Labeling 
    Matthias J.P. van Osch, Matthias Günther, Eric C. Wong
    20 Velocity-Selective Arterial Spin Labeling 
    Eric C. Wong, Lawrence R. Frank
    21 Keys to Robust Arterial Spin Labeling in the Clinical and Research Environment 
    David C. Alsop, Jeroen Hendrikse
    22 “Pick Your Poison”: The Arterial Spin Labeling Shopper’s Guide or Which Method for Which Application? 
    Hanzhang Lu, Matthias Günther, Xavier Golay, Susan R. Hopkins, Fritz Schick, Rebecca J. Theilmann, Petros Martirosian, Christina Schraml, Andreas Boss

    Section 5: Dynamic Contrast-Enhanced MR and CT
    23 The Basic Principles of Dynamic Contrast–Enhanced Magnetic Resonance Imaging 
    Julio Cárdenas-Rodríguez, Xia Li, Jennifer G. Whisenant, Stephanie Barnes, Rudolf Stollberger, John C. Gore, Thomas E. Yankeelov

    Section 6: Computational Methods
    24 Convolution Model 
    Peter Gall, Ting-Yim Lee, Roland Bammer
    25 Practical Aspects of Deconvolution 
    Fernando Calamante, Matus Straka, Lisa Willats
    26 Arterial Input Function and Venous Output Function 
    Soren Christensen, Matus Straka, Ting-Yim Lee
    27 The Bookend Technique and Other Scaling Techniques 
    Jessy J. Mouannes-Srour, Timothy J. Carroll
    28 The Effects of Contrast Agent Extravasation Perfusion Parameter Maps Derived from Dynamic Susceptibility Contrast Magnetic Resonance Imaging 
    Kathleen M. Schmainda, Eric S. Paulson, Jerrold L. Boxerman
    29 Pharmacokinetic Models for Dynamic Contrast-Enhanced Computed Tomography and Magnetic Resonance Imaging 
    Steven Sourbron, Ting-Yim Lee
    30 Blood Flow Quantitation with Arterial Spin Labeling 
    Laura M. Parkes, Hanzhang Lu, Esben T. Petersen
    31 Perfusion Confusion: What Is Perfusion and What Do We Measure? 
    Richard B. Buxton

    Section 7: Comparability
    32 Dynamic Susceptibility Contrast Magnetic Resonance Imaging Calibration Between Sites and Comparability 
    Jeffry R. Alger, Matthias J.P. van Osch, Thoralf Niendorf, Pamela W. Schaefer, Kohsuke Kudo, Roland Bammer
    33 CT Perfusion Imaging: Calibration and Comparability 
    Benjamin Zussman, Kohsuke Kudo, Adam Flanders, Vicky Goh, Pamela W. Schaefer, Roland Bammer, Max Wintermark
    34 Arterial Spin Labeling Calibration Between Sites and Comparability 
    Thomas T. Liu, Matthias J.P. van Osch, Matthias Günther, Xavier Golay
    35 Dynamic Contrast-Enhanced Magnetic Resonance Imaging Calibration Between Sites and Comparability 
    Gudrun Zahlmann, Peter Gall, Sandeep N. Gupta, Thorsten Persigehl

    PART II • CLINICAL APPLICATIONS
    Section 1: Setting the Stage

    36 Normal Blood Flow Values in Organs 
    Shalini A. Amukotuwa, Didem Aksoy, Roland Bammer
    37 Information about MR and CT Contrast Agents 
    Roland Bammer
    38 General Patient Dressing for Magnetic Resonance and Computed Tomography Studies 
    Lior Molvin, Teresa Nelson, Christoph Zorich, Roland Bammer, Shalini A. Amukotuwa
    39 Arterial Spin Labeling Acquisition Protocols 
    Youngkyoo Jung, Joseph A. Maldjian, Christopher T. Whitlow, Greg Zaharchuk, Shalini A. Amukotuwa, Jeroen Hendrikse

    Section 2: Cerebrovascular Diseases
    40 Cerebrovascular Anatomy and Regional Blood Supply 
    Robert Vollmann, Josef Simbrunner, Michael Augustin
    41 Normal and Abnormal Physiology of Cerebral Blood Flow 
    Andrew Bivard, Mark Parsons
    42 Acute Stroke: Intra-Arterial and Intravenous Treatment Options 
    Tudor Jovin, Michael P. Marks, Roland Bammer
    43 Perfusion Profiles for Favorable and Unfavorable Outcomes 
    Maarten G. Lansberg, Nishant K. Mishra, Soren Christensen, Bruce C. V. Campbell
    44 Collateral Flow, Luxury Perfusion, and Vasospasm: Clinical Applications and Theoretical Principles 
    Mateo Calderon-Arnulphi, Peter D. Schellinger, David S. Liebeskind
    45 The Role of Multimodal Brain Imaging in Clinical Stroke Trials 
    Bruce C. V. Campbell, Geoffrey A. Donnan, Stephen M. Davis
    46 Lacunar Stroke and Microangiopathy 
    Brian D. Zipser, Bhavya Rehani, Pamela W. Schaefer
    47 Perfusion and Dynamic Contrast-Enhanced Imaging in Hemorrhage 
    Didem Aksoy, Andrea Kassner, Jason Hom, Karen Hirsch, Christine Wijman, Chitra Venkatasubramanian
    48 Perfusion Imaging in Chronic Occlusive Disease of Intracranial Vessels and Vascular Reserve Testing 
    Jeroen Hendrikse, Greg Zaharchuk
    49 Perfusion in Chronic Carotid Artery Disease 
    Nolan S. Hartkamp, Jeroen Hendrikse, Reinoud P. H. Bokkers
    50 Transient Ischemic Attack and Perfusion Imaging 
    Shyam Prabhakaran, Jonathan Kleinman, Greg Zaharchuk, Jean-Marc Olivot
    51 Arterial Spin Labeling in Arteriovenous Malformations 
    Ronald L. Wolf, Jeffrey M. Pollock
    52 Perfusion in Dural Arteriovenous Fistulas 
    Shalini A. Amukotuwa, Roland Bammer
    53 Migraine and Seizures 
    Hongwu Zeng, Christian La, Veena A. Nair, Vivek Prabhakaran, Howard A. Rowley
    54 Pediatric Stroke and Congenital Disease 
    Seena Dehkharghani, Nilesh K. Desai

    Section 3: Tumors
    55 Tumor Vasculature: Structure and Function 
    Janice A. Nagy, Amjad Husain, Shou-Ching Jaminet, Ann M. Dvorak, Harold F. Dvorak
    56 Response Evaluation Criteria In Solid Tumors (RECIST) and World Health Organization (WHO) Criteria for Cancer Progression 
    Syed Mahmood, Saleha Sajid
    57 De Novo Brain Tumor Evaluation: Use of Individual and Combined DSC, DCE, and ASL for Diagnosis and Differentiation 
    Jalal B. Andre, Pia C. Sundgren, Mark S. Shiroishi, Meng Law
    58 Predicting Prognosis, Therapy Selection, Guidance, and Treatment Monitoring 
    Mark S. Shiroishi, Jesse G. A. Jones, Jalal B. Andre, Marco Essig, Pia C. Sundgren, Paul E. Kim, Meng Law
    59 Contrast Enhancement: Differentiating Tumor Recurrence from Non-neoplastic Tissue Following Intervention
    (Surgery, Chemotherapy, Radiotherapy) 
    Jalal B. Andre, James Fink, Mark S. Shiroishi, Pia C. Sundgren, Sarah Foster, Alexander Lerner, Michael T. Booker
    60 Perfusion Imaging Using Magnetic Resonance Imaging and Computed Tomography in Head and Neck Cancer 
    Gaurang Shah, Zoran Rumboldt, Yonggang Lu, Amita Shukla-Dave, Harish Poptani, Suresh Mukherji
    61 Female Pelvis 
    Tristan Barrett, Andrew B. Gill, Evis Sala
    62 Lung Cancer 
    Vicky Goh, Peter Hoskin
    63 Breast Cancer
    Bruce L. Daniel
    64 Prostate Cancer 
    Olivier Rouvière, Peter L. Choyke, Baris Turkbey, Henkjan Huisman
    65 Perfusion Imaging in Liver and Pancreas 
    Se Hyung Kim, Dow-Mu Koh, Jürgen K. Willmann
    66 Renal Tumors 
    Mark A. Rosen, Stephen M. Keefe, Priti Lal, William M. F. Lee
    67 Gastrointestinal Imaging 
    Nyree Griffin, Lee Grant, Vicky Goh
    68 Clinical Applications of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Musculoskeletal Tumors 
    June S. Taylor, Wilburn E. Reddick, Robert J. Canter
    69 Oncology Drug Development 
    Edward Ashton, Philip F. Murphy, James O’Connor
    70 Myocardial Perfusion and Permeability 
    Michael Jerosch-Herold, Krishna Nayak, Tim Leiner, Rozemarijn Vliegenthart, Sven Plein

    Section 4: Miscellaneous
    71 Dementia and Degenerative Diseases 
    Norbert Schuff
    72 Perfusion in Pharmacologic Imaging 
    Fernando O. Zelaya, María A. Fernández-Seara, Kevin Black, Steven C.R. Williams, Mitul A. Mehta
    73 Perfusion and Dynamic Contrast-Enhanced Imaging in White Matter Disease 
    Matilde Inglese, Jens Würfel, Glyn Johnson
    74 Cerebral Perfusion Studies in Substance Abuse and Dependence 
    Linda Chang, Santosh Yadav, Thomas Ernst
    75 Perfusion and Dynamic Contrast-Enhanced Imaging to Study Renal Function 
    Richard A. Jones, Shreyas Vasanawala, Damien Grattan-Smith
    76 Arterial Spin Labeling for Functional Neuroimaging 
    Thomas T. Liu
    77 Vascular Response to Hypoxia and Hypercapnia 
    Daniel P. Bulte, Molly G. Bright, Franklyn A. Howe, Douglas R. Corfield
    78 Retinal and Choroidal Blood Flow 
    Timothy Q. Duong, Eric R. Muir
    79 Vascular-Space-Occupancy Magnetic Resonance Imaging 
    Jun Hua, Ying Cheng, Peter C.M. van Zijl

    Section 5: History
    80 Computed Tomography Perfusion Imaging:How Did It All Start? 
    Leon Axel
    81 The History of Dynamic Susceptibility Contrast Imaging: An Interview with Roland Bammer 
    Bruce R. Rosen
    82 The Early History of Arterial Spin Labeling Magnetic Resonance Imaging: 1992 to 2000 
    John A. Detre
    83 The Early Days of Modeling Contrast Agent Kinetics 
    Paul S. Tofts
  • Editorial Reviews
    'an in-depth discussion of the physics behind different MR and CT techniques'

    'a very detailed discussion of physics techniques'

    'carve out detailed physics explanations from the main part of the book by placing them in "Geek Boxes."'

    -Doodys Publishers' Club, July 1, 2016
     
  • Review
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