Home / Allied Health / Foye's Principles of Medicinal Chemistry

Foye's Principles of Medicinal Chemistry

9781609133450
ISBN/ISSN
9781609133450
Publication Date
March 8, 2012
2012-03-8
Availablity
IN STOCK
9781609133450
Preview link
Rights Link
$ USD 107.99 $107.99
Quantity
System.String
""
Item already added to cart.

Share

Sorry! Promocode will not apply for this product.

System.Collections.Generic.List`1[[System.Object, mscorlib, Version=4.0.0.0, Culture=neutral, PublicKeyToken=b77a5c561934e089]]
[{"attributeFQN":"tenant~abouttheauthors","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextArea","dataType":"String","usageType":"Property","dataTypeSequence":6,"name":"About the Authors","description":"","searchDisplayValue":true},"values":[{"value":"2603359","stringValue":"\u003cdl\u003e\u003cdt\u003eThomas L Lemke PhD\u003c/dt\u003e\u003cdd\u003e\u003cDIV\u003eAssociate Dean for Professional Programs and Professor of Medicinal Chemistry, University of Houston, Houston, TX\u003c/DIV\u003e\u003c/dd\u003e\u003c/dl\u003e\u003cdl\u003e\u003cdt\u003eVictoria F Roche PhD\u003c/dt\u003e\u003cdd\u003e\u003cdiv\u003eSenior Associate Dean, School of Pharmacy and Health Professions, Creighton University, Omaha, NE\u003c/div\u003e\u003c/dd\u003e\u003c/dl\u003e\u003cdl\u003e\u003cdt\u003eDavid A Williams PhD\u003c/dt\u003e\u003cdd\u003e\u003cDIV\u003eEmeritus Professor of Chemistry, Massachusetts College of Pharmacy and Health Sciences, Boston, MA\u003c/DIV\u003e\u003c/dd\u003e\u003c/dl\u003e\u003cdl\u003e\u003cdt\u003eS. W Zito PhD\u003c/dt\u003e\u003cdd\u003e\u003cDIV\u003eCollege of Pharmacy and Allied Health Professions, St. John\u0027s University, Jamaica, NY\u003c/DIV\u003e\u003c/dd\u003e\u003c/dl\u003e"}]},{"attributeFQN":"tenant~features","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextArea","dataType":"String","usageType":"Property","dataTypeSequence":7,"name":"Features","description":"","searchDisplayValue":true},"values":[{"value":"2603362","stringValue":"\u003cdiv\u003e\u003cul\u003e    \u003cli\u003eNew! Membrane Drug Transporters chapter\u003c/li\u003e    \u003cli\u003eNew! Nutrition and Obesity chapter\u003c/li\u003e    \u003cli\u003eExpanded Anesthetics chapter\u003c/li\u003e    \u003cli\u003eAbbreviations list includes full terms spelled out\u003c/li\u003e    \u003cli\u003eClinical Scenarios: an initial scenario is introduced at the beginning of each chapter. Then, applying the material presented and drugs discussed in the chapter, an Outcome and Chemical Analysis of the Scenario is provided at the end of the chapter.\u003c/li\u003e    \u003cli\u003eSidebar boxes provide additional information related to material discussed within the text.\u003c/li\u003e    \u003cli\u003eClinical Significance boxes explain how chapter content is related to effective pharmaceutical care.\u003c/li\u003e    \u003cli\u003eCase Studies at the end of each chapter ask students to evaluate a patient and apply knowledge of medicinal chemistry to choose the most appropriate therapeutic option. \u003c/li\u003e\u003c/ul\u003e\u003c/div\u003e"}]},{"attributeFQN":"tenant~ean13","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":8,"name":"ean13","description":"","searchableInStorefront":true,"searchDisplayValue":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"9781609133450","stringValue":"9781609133450"}]},{"attributeFQN":"tenant~producttype","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"Predefined","inputType":"List","dataType":"String","usageType":"Property","dataTypeSequence":10,"name":"Product Type","description":"","searchableInStorefront":true,"searchDisplayValue":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"Book","stringValue":"Book"}]},{"attributeFQN":"tenant~publicationdate","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":11,"name":"Publication Date","description":"","searchableInStorefront":true,"searchDisplayValue":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"2012-03-08","stringValue":"2012-03-08"}]},{"attributeFQN":"tenant~format","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"Predefined","inputType":"List","dataType":"String","usageType":"Property","dataTypeSequence":14,"name":"Format","description":"","searchableInStorefront":true,"searchDisplayValue":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"HC-Printed Cover","stringValue":"HC-Printed Cover"}]},{"attributeFQN":"tenant~isbn10","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":15,"name":"isbn10","description":"","searchableInStorefront":true,"searchDisplayValue":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"1609133455","stringValue":"1609133455"}]},{"attributeFQN":"tenant~edition","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":16,"name":"Edition","description":"","searchDisplayValue":true},"values":[{"value":"7","stringValue":"7"}]},{"attributeFQN":"tenant~pagecount","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":17,"name":"Page count","description":"","searchDisplayValue":true},"values":[{"value":"1520","stringValue":"1520"}]},{"attributeFQN":"tenant~weight","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":18,"name":"Weight","description":"","searchDisplayValue":true},"values":[{"value":"7.30","stringValue":"7.30"}]},{"attributeFQN":"tenant~length","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":19,"name":"Length","description":"","searchDisplayValue":true},"values":[{"value":"10.875","stringValue":"10.875"}]},{"attributeFQN":"tenant~width","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":20,"name":"Width","description":"","searchDisplayValue":true},"values":[{"value":"8.375","stringValue":"8.375"}]},{"attributeFQN":"tenant~inventorystatus","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":21,"name":"Inventory status","description":"","searchDisplayValue":true},"values":[{"value":"IN STOCK","stringValue":"IN STOCK"}]},{"attributeFQN":"tenant~isprimary","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"YesNo","dataType":"Bool","usageType":"Property","dataTypeSequence":1,"name":"IsPrimary","description":"","searchableInStorefront":true,"searchDisplayValue":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":true}]},{"attributeFQN":"tenant~workkey","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":23,"name":"Workkey","description":"","searchableInStorefront":true,"searchDisplayValue":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"1209809","stringValue":"1209809"}]},{"attributeFQN":"tenant~editiontypecode","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":27,"name":"Edition typecode","description":"","searchDisplayValue":true},"values":[{"value":"7","stringValue":"7"}]},{"attributeFQN":"tenant~statuscode","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":30,"name":"Status Code","description":"","searchDisplayValue":true},"values":[{"value":"1","stringValue":"1"}]},{"attributeFQN":"tenant~statusdescription","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":31,"name":"Status Description","description":"","searchDisplayValue":true},"values":[{"value":"IP - Available- In Stock","stringValue":"IP - Available- In Stock"}]},{"attributeFQN":"tenant~lippincottdirect","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":32,"name":"Lippincott Direct","description":"","searchDisplayValue":true},"values":[{"value":"NO","stringValue":"NO"}]},{"attributeFQN":"tenant~booksample","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":33,"name":"Book Sample","description":"","searchDisplayValue":true},"values":[{"value":"YES","stringValue":"YES"}]},{"attributeFQN":"tenant~digitalproduct","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":34,"name":"Digital Product","description":"","searchDisplayValue":true},"values":[{"value":"NO","stringValue":"NO"}]},{"attributeFQN":"tenant~itemnumber","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":35,"name":"Item number","description":"","searchDisplayValue":true},"values":[{"value":"1-60913-345-5","stringValue":"1-60913-345-5"}]},{"attributeFQN":"tenant~classcode","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":36,"name":"Class Code","description":"","searchDisplayValue":true},"values":[{"value":"1","stringValue":"1"}]},{"attributeFQN":"tenant~classdescription","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":37,"name":"Class Description","description":"","searchDisplayValue":true},"values":[{"value":"Title","stringValue":"Title"}]},{"attributeFQN":"tenant~publishercode","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":38,"name":"Publisher Code","description":"","searchDisplayValue":true},"values":[{"value":"17","stringValue":"17"}]},{"attributeFQN":"tenant~publisherdescription","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":39,"name":"Publisher Description","description":"","searchDisplayValue":true},"values":[{"value":"LWW (PE)","stringValue":"LWW (PE)"}]},{"attributeFQN":"tenant~imprintcode","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":40,"name":"Imprint Code","description":"","searchDisplayValue":true},"values":[{"value":"45","stringValue":"45"}]},{"attributeFQN":"tenant~imprintdescription","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":41,"name":"Imprint Description","description":"","searchDisplayValue":true},"values":[{"value":"LWW","stringValue":"LWW"}]},{"attributeFQN":"tenant~bookkey","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":45,"name":"Bookkey","description":"","searchDisplayValue":true},"values":[{"value":"1209809","stringValue":"1209809"}]},{"attributeFQN":"tenant~tableofcontents","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextArea","dataType":"String","usageType":"Property","dataTypeSequence":46,"name":"Table of contents","description":"","searchDisplayValue":true},"values":[{"value":"2603361","stringValue":"\u003cdiv\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eHistorical Perspective of Medicinal Chemistry \u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                JOHN L. NEUMEYER\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e\u003cb\u003ePART I: PRINCIPLES OF DRUG DISCOVERY \u003c/b\u003e\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 1 Drug Discovery from Natural Products\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                A. DOUGLAS KINGHORN\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 2 Drug Design and Relationship of Functional Groups to Pharmacologic Activity\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                JAMES J. KNITTEL\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 3 Molecular Modeling and In Silico Drug Design \u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                ROBERT J. DOERKSEN\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 4 Role of Physicochemical Properties and Pharmacokinetics in Drug Discovery\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                SUNIL S. JAMBHEKAR\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 5 Drug Metabolism\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eDAVID A. WILLIAMS\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 6 Membrane Drug Transporters\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                MARILYN MORRIS\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 7 Pharmaceutical Biotechnology\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                RONALD E. REID\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 8 Receptors as Targets for Drug Discovery  \u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                TIMOTHY A. MAHER AND DAVID A. JOHNSON\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 9 Drug Discovery Through Enzyme Inhibition \u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                STEPHEN KERR\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e\u003cb\u003ePART II: DRUG RECEPTORS AFFECTING NEUROTRANSMISSION AND ENZYMES AS CATALYTIC RECEPTORS \u003c/b\u003e\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 10 Cholinergic Receptors and Drugs Affecting Cholinergic Neurotransmission \u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eE. KIM FIFER\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 11 Adrenergic Receptors and Drugs Affecting Adrenergic neurotransmission \u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                ROBERT K. GRIFFITH\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 12 Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eRICHARD A. GLENNON AND MALGORZATA DUKAT-GLENNON\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 13 Amino Acid Neurotransmitters and Drugs Affecting Amino Acid Neurotransmission \u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                TIMOTHY J. MAHER\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e\u003cb\u003ePART III: PHARMACODYNAMIC AGENTS \u003c/b\u003e\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e\u003cb\u003eSection 1: Drugs Affecting Central Nervous System \u003c/b\u003e\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 14 Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eRAYMOND G. BOOTH\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 15 Psychotherapeutic Drugs: Antipsychotic and Anxiolytics\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                RAYMOND G. BOOTH\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 16 Sedative-Hypnotics \u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eNADER H. MONIRI\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 17 Anesthetics : General and Local Anesthetics  \u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                TIMOTHY J. MAHER and MATTHIAS C. LU\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 18 Antiseizure Agents\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                BARBARA LEDUC\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 19 Antidepressants \u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                DAVID A. WILLIAMS\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 20 CNS Stimulants and Drugs of Abuse\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                RICHARD A. GLENNON\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 21 Opioid Analgesics\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                CHRISTOPHER   MCCURDY\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e\u003cb\u003eSection 2: Drugs Affecting the Cardiovascular System \u003c/b\u003e\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 22 Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eAHMED S. MEHANNA\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 23 Diuretics\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003ePETER HARVISON\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 24 Angiotensin-Converting Enzyme Inhibitors, Antagonists and Calcium Blockers\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eMARC HARROLD\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 25 Central and Peripheral Sympatholytics and Vasodilators\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eDAVID A. WILLIAMS\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 26 Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eMARC HARROLD\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 27 Antithrombotics, Thrombolytics, Antiplatelets, and Coagulants,\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eMATTHIAS C. LU and Thomas Lemke\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e \u003cb\u003eSection 3: Drugs Affecting the Hormonal Systems \u003c/b\u003e\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 28 Drugs for the Treatment of Diabetes\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                S William Zito\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 29 Adrenocorticoids\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eDUANE D. MILLER, ROBERT W. BRUEGGEMEIER AND JAMES T. DALTON\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 30 Thyroid Function and Thyroid Drugs\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eALI R. BANIJAMALI\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 31 Calcium Homeostasis\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eROBIN M. ZAVOD\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e\u003cb\u003eSection 4: Drugs Affecting Inflammation and the Immune Systems \u003c/b\u003e\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 32 Nonsteroidal Anti-Inflammatory Drugs\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eRONALD BORNE\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 33 Antihistamines and Related Antiallergic and Antiulcer Agents\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eWENDEL L.NELSON\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e\u003cb\u003eSection 5: Chemotherapeutic Agents \u003c/b\u003e\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 34 Antibiotics and Antimicrobial Agents\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eELMER J. GENTRY\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 35 Antiparasitic Agents\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eTHOMAS L. LEMKE\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 36 Antifungal Agents\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eROBERT K. GRIFFITH\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 37 Antimycobacterial Agents\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eTHOMAS L. LEMKE\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 38 Cancer and Chemotherapy\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eVICTORIA F. ROCHE\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 39 Antiviral Agents and Protease Inhibitors\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e                PATRICK WOOSTER\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003e\u003cb\u003ePART IV: DISEASE STATE MANAGEMENT \u003c/b\u003e\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 40 Asthma and Chronic Obstructive Pulmonary Disease 1230\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eS. WILLIAM ZITO\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 41 Men\u0026rsquo;s Health\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eDUANE D. MILLER, ROBERT W. BRUEGGEMEIER, AND JAMES T. DALTON\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 42 Women\u0026rsquo;s Health\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; text-indent: 0.5in; margin: 0in 0in 10pt\u0027\u003eROBIN M. ZAVOD\u003c/div\u003e\u003cdiv style=\u0027line-height: normal; margin: 0in 0in 10pt\u0027\u003eChapter 43 Obesity and Nutrition\u003c/div\u003e                THOMAS LEMKE AND DAVID WILLIAMS\u003c/div\u003e"}]},{"attributeFQN":"tenant~medicine-role","isHidden":false,"isMultiValue":true,"attributeDetail":{"valueType":"Predefined","inputType":"List","dataType":"String","usageType":"Property","dataTypeSequence":47,"name":"Medicine-Role","description":"","searchableInStorefront":true,"searchDisplayValue":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"medicalstudents","stringValue":"Medical Students"}]},{"attributeFQN":"tenant~allied-specialty","isHidden":false,"isMultiValue":true,"attributeDetail":{"valueType":"Predefined","inputType":"List","dataType":"String","usageType":"Property","dataTypeSequence":52,"name":"Allied-Specialty","description":"","searchableInStorefront":true,"searchDisplayValue":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"pharmacy","stringValue":"Pharmacy"}]},{"attributeFQN":"tenant~authors","isHidden":false,"isMultiValue":true,"attributeDetail":{"valueType":"Predefined","inputType":"List","dataType":"String","usageType":"Property","dataTypeSequence":53,"name":"Authors","description":"","searchableInStorefront":true,"searchDisplayValue":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"thomasllemkephd","stringValue":"Thomas L. Lemke PhD"},{"value":"davidawilliamsphd","stringValue":"David A. Williams PhD"},{"value":"swzitophd","stringValue":"S. W Zito PhD"},{"value":"victoriafrochephd","stringValue":"Victoria F. Roche PhD"}]},{"attributeFQN":"tenant~copyright-exclusion","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"YesNo","dataType":"Bool","usageType":"Property","dataTypeSequence":2,"name":"Copyright_Exclusion","description":"","searchableInStorefront":true,"searchDisplayValue":true},"values":[{"value":false}]},{"attributeFQN":"tenant~warehouse175","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":54,"name":"Warehouse175","description":"","searchDisplayValue":true},"values":[{"value":"665","stringValue":"665"}]},{"attributeFQN":"tenant~lwweligible","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":58,"name":"LWW Eligible","description":"","searchDisplayValue":true},"values":[{"value":"YES","stringValue":"YES"}]},{"attributeFQN":"com.mozu.bvconversations~bazaarvoice-category","isHidden":true,"isMultiValue":false,"attributeDetail":{"valueType":"Predefined","inputType":"List","dataType":"String","usageType":"Property","dataTypeSequence":59,"name":"Bazaarvoice Category","description":"","searchableInStorefront":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"3","stringValue":"3-Allied Health"}]},{"attributeFQN":"tenant~illustrationcount","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":60,"name":"Illustration count","description":"","searchDisplayValue":true},"values":[{"value":"271093","stringValue":"1739"}]},{"attributeFQN":"tenant~tablecount","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":61,"name":"table count","description":"","searchDisplayValue":true},"values":[{"value":"271094","stringValue":"60"}]},{"attributeFQN":"tenant~publicationyear","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextBox","dataType":"String","usageType":"Property","dataTypeSequence":62,"name":"Publication Year","description":"","searchableInStorefront":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"2012","stringValue":"2012"}]},{"attributeFQN":"tenant~buttontype","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"Predefined","inputType":"List","dataType":"String","usageType":"Property","dataTypeSequence":64,"name":"buttontype","description":"","searchableInStorefront":true,"searchDisplayValue":true,"allowFilteringAndSortingInStorefront":true},"values":[{"value":"addtocart","stringValue":"addtocart"}]},{"attributeFQN":"tenant~authorslist","isHidden":false,"isMultiValue":false,"attributeDetail":{"valueType":"AdminEntered","inputType":"TextArea","dataType":"String","usageType":"Property","dataTypeSequence":67,"name":"AuthorsList","description":"","searchableInStorefront":true,"searchDisplayValue":true},"values":[{"value":"2603360","stringValue":"Thomas L Lemke PhD,Victoria F Roche PhD,David A Williams PhD,S. W Zito PhD"}]}]
  • Description

    Acclaimed by students and instructors alike, Foye's Principles of Medicinal Chemistry is now in its Seventh Edition, featuring updated chapters plus new material that meets the needs of today's medicinal chemistry courses. This latest edition offers an unparalleled presentation of drug discovery and pharmacodynamic agents, integrating principles of medicinal chemistry with pharmacology, pharmacokinetics, and clinical pharmacy.

    All the chapters have been written by an international team of respected researchers and academicians. Careful editing ensures thoroughness, a consistent style and format, and easy navigation throughout the text.

  • Specs
    Edition
    7
    ISBN/ISSN
    9781609133450
    Product Format
    HC-Printed Cover
    Trim Size
    8.375 x 10.875
    Pages
    1520
    Illustration
    1739
    Table
    60
    Publication Date
    March 8, 2012
    Weight
    7.30
  • About The Author(s)
    Thomas L Lemke PhD
    Associate Dean for Professional Programs and Professor of Medicinal Chemistry, University of Houston, Houston, TX
    Victoria F Roche PhD
    Senior Associate Dean, School of Pharmacy and Health Professions, Creighton University, Omaha, NE
    David A Williams PhD
    Emeritus Professor of Chemistry, Massachusetts College of Pharmacy and Health Sciences, Boston, MA
    S. W Zito PhD
    College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, NY
  • Features
    • New! Membrane Drug Transporters chapter
    • New! Nutrition and Obesity chapter
    • Expanded Anesthetics chapter
    • Abbreviations list includes full terms spelled out
    • Clinical Scenarios: an initial scenario is introduced at the beginning of each chapter. Then, applying the material presented and drugs discussed in the chapter, an Outcome and Chemical Analysis of the Scenario is provided at the end of the chapter.
    • Sidebar boxes provide additional information related to material discussed within the text.
    • Clinical Significance boxes explain how chapter content is related to effective pharmaceutical care.
    • Case Studies at the end of each chapter ask students to evaluate a patient and apply knowledge of medicinal chemistry to choose the most appropriate therapeutic option. 
  • Table of contents
    Historical Perspective of Medicinal Chemistry 
                    JOHN L. NEUMEYER
    PART I: PRINCIPLES OF DRUG DISCOVERY
    Chapter 1 Drug Discovery from Natural Products
                    A. DOUGLAS KINGHORN
    Chapter 2 Drug Design and Relationship of Functional Groups to Pharmacologic Activity
                    JAMES J. KNITTEL
    Chapter 3 Molecular Modeling and In Silico Drug Design 
                    ROBERT J. DOERKSEN
    Chapter 4 Role of Physicochemical Properties and Pharmacokinetics in Drug Discovery
                    SUNIL S. JAMBHEKAR
    Chapter 5 Drug Metabolism
    DAVID A. WILLIAMS
    Chapter 6 Membrane Drug Transporters
                    MARILYN MORRIS
    Chapter 7 Pharmaceutical Biotechnology
                    RONALD E. REID
    Chapter 8 Receptors as Targets for Drug Discovery  
                    TIMOTHY A. MAHER AND DAVID A. JOHNSON
    Chapter 9 Drug Discovery Through Enzyme Inhibition 
                    STEPHEN KERR
    PART II: DRUG RECEPTORS AFFECTING NEUROTRANSMISSION AND ENZYMES AS CATALYTIC RECEPTORS
    Chapter 10 Cholinergic Receptors and Drugs Affecting Cholinergic Neurotransmission 
    E. KIM FIFER
    Chapter 11 Adrenergic Receptors and Drugs Affecting Adrenergic neurotransmission 
                    ROBERT K. GRIFFITH
    Chapter 12 Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission
    RICHARD A. GLENNON AND MALGORZATA DUKAT-GLENNON
    Chapter 13 Amino Acid Neurotransmitters and Drugs Affecting Amino Acid Neurotransmission 
                    TIMOTHY J. MAHER
    PART III: PHARMACODYNAMIC AGENTS
    Section 1: Drugs Affecting Central Nervous System
    Chapter 14 Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents
    RAYMOND G. BOOTH
    Chapter 15 Psychotherapeutic Drugs: Antipsychotic and Anxiolytics
                    RAYMOND G. BOOTH
    Chapter 16 Sedative-Hypnotics 
    NADER H. MONIRI
    Chapter 17 Anesthetics : General and Local Anesthetics  
                    TIMOTHY J. MAHER and MATTHIAS C. LU
    Chapter 18 Antiseizure Agents
                    BARBARA LEDUC
    Chapter 19 Antidepressants 
                    DAVID A. WILLIAMS
    Chapter 20 CNS Stimulants and Drugs of Abuse
                    RICHARD A. GLENNON
    Chapter 21 Opioid Analgesics
                    CHRISTOPHER   MCCURDY
    Section 2: Drugs Affecting the Cardiovascular System
    Chapter 22 Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs
    AHMED S. MEHANNA
    Chapter 23 Diuretics
    PETER HARVISON
    Chapter 24 Angiotensin-Converting Enzyme Inhibitors, Antagonists and Calcium Blockers
    MARC HARROLD
    Chapter 25 Central and Peripheral Sympatholytics and Vasodilators
    DAVID A. WILLIAMS
    Chapter 26 Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis
    MARC HARROLD
    Chapter 27 Antithrombotics, Thrombolytics, Antiplatelets, and Coagulants,
    MATTHIAS C. LU and Thomas Lemke
     Section 3: Drugs Affecting the Hormonal Systems
    Chapter 28 Drugs for the Treatment of Diabetes
                    S William Zito
    Chapter 29 Adrenocorticoids
    DUANE D. MILLER, ROBERT W. BRUEGGEMEIER AND JAMES T. DALTON
    Chapter 30 Thyroid Function and Thyroid Drugs
    ALI R. BANIJAMALI
    Chapter 31 Calcium Homeostasis
    ROBIN M. ZAVOD
    Section 4: Drugs Affecting Inflammation and the Immune Systems
    Chapter 32 Nonsteroidal Anti-Inflammatory Drugs
    RONALD BORNE
    Chapter 33 Antihistamines and Related Antiallergic and Antiulcer Agents
    WENDEL L.NELSON
    Section 5: Chemotherapeutic Agents
    Chapter 34 Antibiotics and Antimicrobial Agents
    ELMER J. GENTRY
    Chapter 35 Antiparasitic Agents
    THOMAS L. LEMKE
    Chapter 36 Antifungal Agents
    ROBERT K. GRIFFITH
    Chapter 37 Antimycobacterial Agents
    THOMAS L. LEMKE
    Chapter 38 Cancer and Chemotherapy
    VICTORIA F. ROCHE
    Chapter 39 Antiviral Agents and Protease Inhibitors
                    PATRICK WOOSTER
    PART IV: DISEASE STATE MANAGEMENT
    Chapter 40 Asthma and Chronic Obstructive Pulmonary Disease 1230
    S. WILLIAM ZITO
    Chapter 41 Men’s Health
    DUANE D. MILLER, ROBERT W. BRUEGGEMEIER, AND JAMES T. DALTON
    Chapter 42 Women’s Health
    ROBIN M. ZAVOD
    Chapter 43 Obesity and Nutrition
                    THOMAS LEMKE AND DAVID WILLIAMS
  • Review