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Clinical Epidemiology

How to Do Clinical Practice Research
Publication Date
September 13, 2005
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  • Description
    Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product.

    The Third Edition of this popular text focuses on clinical-practice research methods. It is written by clinicians with experience in generating and answering researchable questions about real-world clinical practice and health care—the prevention, treatment, diagnosis, prognosis, and causes of diseases, the measurement of quality of life, and the effects of innovations in health services. The book has a problem-oriented and protocol-based approach and is written at an introductory level, emphasizing key principles and their applications.

    A bound-in CD-ROM contains the full text of the book to help the reader locate needed information.

  • Specs
    Product Format
    Publication Date
    September 13, 2005
  • About The Author(s)
    R. Brian Haynes
    David L. Sackett OC, MD, FRSC, FRCP (Canad
    Director, Kilgore S. Trout Research and Education Centre at Irish Lake, Canada; Once Professor of Clinical Epidemiology and Medicine at McMaster University, and of Medicine at the University of Oxford; Adjunct Professor of Medicine, University of Ottawa; and Honorary Professor of Clinical Epidemiology, West China Medical College
    Gordon H. Guyatt MD, MSc, FRCPC, FACCP
    Professor of Clinical Epidemiology and Medicine, Michael G. DeGroote School of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
    Peter Tugwell
  • Table of contents

      PART ONE: Performing Clinical Research

    1. Forming Research Questions.... 3
    2. Conducting Systematic Reviews.... 15
    3. Finding Information About the Burden of Disease.... 49
    4. An Introduction to Performing Therapeutic Trials.... 59
    5. The Tactics of Performing Therapeutic Trials.... 66
    6. The Principles Behind the Tactics of Performing Therapeutic Trials.... 173
    7. Testing Quality Improvement Interventions.... 244
    8. Evaluating Diagnostic Tests.... 273
    9. Determining Prognosis and Creating Clinical Decision Rules.... 323
    10. Assessing Claims of Causation.... 356
    11. Generating Outcome Measurements, Especially for Quality of Life.... 388

      PART TWO: Becoming a Clinical Researcher

    12. Becoming a Successful Clinician-Investigator.... 415
    13. Preparing a Research Protocol to Improve its Chances for Success.... 429
    14. Online Data Collection.... 440
    15. Analyzing Data.... 446
    16. Preparing Reports for Publication and Responding to Reviewers' Comments.... 461
    17. Dealing with the Media.... 474

      Index.... 487
  • Review
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